ID A0A0B2VKB1_TOXCA Unreviewed; 432 AA.
AC A0A0B2VKB1;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative G-protein coupled receptor {ECO:0000313|EMBL:KHN81465.1};
GN Name=GPR158 {ECO:0000313|EMBL:KHN81465.1};
GN ORFNames=Tcan_18961 {ECO:0000313|EMBL:KHN81465.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN81465.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN81465.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN81465.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN81465.1}.
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DR EMBL; JPKZ01001513; KHN81465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2VKB1; -.
DR STRING; 6265.A0A0B2VKB1; -.
DR OMA; CHTKCTW; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR043458; GPR158/179.
DR PANTHER; PTHR32546; G-PROTEIN COUPLED RECEPTOR 158-RELATED; 1.
DR PANTHER; PTHR32546:SF16; G-PROTEIN COUPLED RECEPTOR CG31760-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KHN81465.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 55..287
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|Pfam:PF00003"
FT REGION 385..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 49595 MW; 1A4439B5728C70BD CRC64;
MARDEMSNFG HYSYFGSDDL QCTWTVHGGT RVHARTCCSN QTSLCRDRAQ QGRGILVLFN
AACALLCVLL VPLVFRERRR QHEARGWALM ELFLLGAAAL YSILLLEWLN PAWPTCCLAV
WLRQIGFSTF YGSIVLKIYR NLQEYRVRKA HHVFVKEEDL LKYLFCILAL TTTGLTAWTL
GSWSDTALWR SAWPQCAAQP WSLTWHGYEL LFLLYGMRLC YKARNSSWLE RWQFTVAVCL
EAVITLMANL IRYSIRNSGH SDTLMTVTFV QLHLTVSVNI VIIIAPKFYL VSSESTRRTQ
TLSGSSARAH PSLAKLRDNL LNGTIDFAEV PIVDMNPDDI RAELKRVYTQ LRMYKLKNIY
QDNPHISKRK GGKKSSDKVI KNRRISIPPS SSPKIRRVEE EERSDLTVES APHNVFLSTY
KLQLEPHQSV RV
//
