ID   A0A0B2VUT9_TOXCA        Unreviewed;       944 AA.
AC   A0A0B2VUT9;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Nuclear export mediator factor NEMF-like protein {ECO:0000313|EMBL:KHN85122.1};
GN   Name=Clbn {ECO:0000313|EMBL:KHN85122.1};
GN   ORFNames=Tcan_12632 {ECO:0000313|EMBL:KHN85122.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN85122.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN85122.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN85122.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN85122.1}.
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DR   EMBL; JPKZ01000858; KHN85122.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2VUT9; -.
DR   STRING; 6265.A0A0B2VUT9; -.
DR   OMA; MFLEFFA; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036}.
FT   DOMAIN          499..570
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          844..937
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          715..785
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          799..836
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          308..355
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        715..733
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..785
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        799..830
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   944 AA;  107001 MW;  77705E48B997A821 CRC64;
     MKNRFSTLDV FAAVHDLKAL QGLRVTNVYD IDSKTYLIRL HVADEKCFIM LESGMRLHKS
     SFDWPKAQFP SSFSMKLRKH IKQKRFEKVE QLGVDRIVDM QFGSEDRAAH VIVELYDRGN
     IVLTDHQYTI LNVLRPRTDK DTDVRFAVRE TYPIGNARQE VVVPSKEQLA EMLGRAKKSE
     SLKRALAPST QYGPALVEHS LRSIGIASNS QIGIHISATE EDVQKLSVAM DIAQKVFDEI
     REKRSRGFIV YKLDTRADGV SLESYQEFHP YRFKQCESEN LREFESFSEC VDEYFSKIEL
     QKADQRALNA EREAFKKLEN VKRDQQERIE SLELAQAEKR EMAELIELNS ELVDRALLVI
     RSAIANQAFA YLSFLDTLFG LSWEMIEEMR KKACESGDPV ASAIVGLNLN SNEMLLSLRD
     PYRDDSPPKK VPIDIALSAY QNSRKFHSEK KAAIDKKQKT ISASAKALKS AQLKTKETLA
     TVRARADVVK SRRQMWFEKF FWFVSSENYL VIGGRDAQQN ELLVKRYLRT GDVYVHADVR
     GASSVVIRNK VHGGEIPPKT LNEAGCMAVS RTAPTGEYLT PGSFMIRGKK NFLPSCQLQM
     GFGLMFKLDE DSLEQHRGER KVVAALMEDS GSVSVNNPDE LELEEEIELE ASGSEDEEEE
     AIAVPPETDE QFPDVSLSGI VNVGGAAGEG DEEYSIIQLG PTLGRTRTEN ERAREQFVEE
     SKKKKEATKK ANRPMTIRQK HKVQKIKKKY GDQDEEERRL RAEWLGSKDR ASKRQGDGEV
     KEELGRGEAI RAKELRHQNL ALDADDREQV KPKEKNGENI LRPSAKVKDE EEDVDESDLR
     IMGEEETKML DSLTWKPLSG DNLLYAVVVV APYHTMLNFK YKVKLTPGTG KRGKAAKSAI
     ALFQREKSAS LQEVNLLRVL AVDDQIARNI PGKVRVSAPQ LNKK
//