ID A0A0B2VW81_TOXCA Unreviewed; 639 AA.
AC A0A0B2VW81;
DT 04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Structural maintenance of chromosomes protein 5 {ECO:0000256|ARBA:ARBA00018687};
GN Name=smc5 {ECO:0000313|EMBL:KHN85205.1};
GN ORFNames=Tcan_04178 {ECO:0000313|EMBL:KHN85205.1};
OS Toxocara canis (Canine roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN85205.1, ECO:0000313|Proteomes:UP000031036};
RN [1] {ECO:0000313|EMBL:KHN85205.1, ECO:0000313|Proteomes:UP000031036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN85205.1};
RA Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA Gasser R.B.;
RT "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC5 subfamily.
CC {ECO:0000256|ARBA:ARBA00010171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KHN85205.1}.
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DR EMBL; JPKZ01000843; KHN85205.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B2VW81; -.
DR STRING; 6265.A0A0B2VW81; -.
DR OMA; RFWTSQP; -.
DR Proteomes; UP000031036; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR027131; SMC5.
DR PANTHER; PTHR45916; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR PANTHER; PTHR45916:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031036}.
FT DOMAIN 18..310
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 160..215
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 243..311
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 639 AA; 73088 MW; F8C3457D9F25604D CRC64;
MANLFQNGTP FADGSVTKIR FTNFLSMAEA ELNFGPKLNL IIGPNGSGKS TVICGLCLAL
GGSPKLLGRS EVLSDYVRHG CEKGAVEVNI RDSKESHDRK VELIITKNNH VEYRRDGRKV
TRAEVRSMAM SYGIQVDNPC VFLAQDKVKS FAQQTPELLL DNTEKMCEKE ERSAARMEEA
VKTSEEKLEE AREKLEEVEA EQERTSEEME RRNRQFLDLS DEYRSIYSEL DGLAKADYIS
EAVRQANAKY HETMKNFEAW KEEMEKAEAL LEEYRAKQAD QSANSSVESE KVALKREYEK
WLKKEDELDQ KTNKINAGFS QLRIEKESID RVDLSGRQQF AEKLEIVRAT NPRQRCADAF
AWYEAHKEQF RKPVYVPVLS MTMNYEDSAP YLETVIPSRD LMVFIFGCRE DEQLLADSKH
PWRISSTVVS DEQVAKLSVD QPLPESMRVL GFERTAFQLF TAPPVVKAFL NSVAHLSNIP
IGTEKTKENL DEVCGVLKNT HRLFLAADLK VRLTKSLYRA DISVQTDCLR RNLRYLTAHM
PSHTGGDKLD EASVKQALCS IEQRSQKLRA ELEEVKRVQQ MVATQKEKVR CQLAKIYQKD
KAHGSIGQLL KLAQRKYGFP VFNENFFLCF EPDVYSNFL
//
