ID   A0A0B2VX70_TOXCA        Unreviewed;       279 AA.
AC   A0A0B2VX70;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Protease inhibitor bitisilin-1 {ECO:0000313|EMBL:KHN85932.1};
GN   ORFNames=Tcan_15879 {ECO:0000313|EMBL:KHN85932.1};
OS   Toxocara canis (Canine roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Toxocaridae; Toxocara.
OX   NCBI_TaxID=6265 {ECO:0000313|EMBL:KHN85932.1, ECO:0000313|Proteomes:UP000031036};
RN   [1] {ECO:0000313|EMBL:KHN85932.1, ECO:0000313|Proteomes:UP000031036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PN_DK_2014 {ECO:0000313|EMBL:KHN85932.1};
RA   Zhu X.-Q., Korhonen P.K., Cai H., Young N.D., Nejsum P.,
RA   von Samson-Himmelstjerna G., Boag P.R., Tan P., Li Q., Min J., Yang Y.,
RA   Wang X., Fang X., Hall R.S., Hofmann A., Sternberg P.W., Jex A.R.,
RA   Gasser R.B.;
RT   "Genetic blueprint of the zoonotic pathogen Toxocara canis.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KHN85932.1}.
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DR   EMBL; JPKZ01000714; KHN85932.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B2VX70; -.
DR   STRING; 6265.A0A0B2VX70; -.
DR   OMA; IDICEYY; -.
DR   Proteomes; UP000031036; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   CDD; cd00109; Kunitz-type; 1.
DR   Gene3D; 4.10.75.10; Elafin-like; 1.
DR   Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR   InterPro; IPR036645; Elafin-like_sf.
DR   InterPro; IPR002223; Kunitz_BPTI.
DR   InterPro; IPR036880; Kunitz_BPTI_sf.
DR   InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR   InterPro; IPR008197; WAP_dom.
DR   PANTHER; PTHR10083:SF382; BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10083; KUNITZ-TYPE PROTEASE INHIBITOR-RELATED; 1.
DR   Pfam; PF00014; Kunitz_BPTI; 1.
DR   Pfam; PF00095; WAP; 1.
DR   PRINTS; PR00759; BASICPTASE.
DR   SMART; SM00131; KU; 1.
DR   SMART; SM00217; WAP; 1.
DR   SUPFAM; SSF57362; BPTI-like; 1.
DR   SUPFAM; SSF57256; Elafin-like; 1.
DR   PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR   PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR   PROSITE; PS51390; WAP; 1.
PE   4: Predicted;
KW   Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031036};
KW   Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}.
FT   DOMAIN          108..162
FT                   /note="WAP"
FT                   /evidence="ECO:0000259|PROSITE:PS51390"
FT   DOMAIN          170..220
FT                   /note="BPTI/Kunitz inhibitor"
FT                   /evidence="ECO:0000259|PROSITE:PS50279"
SQ   SEQUENCE   279 AA;  29435 MW;  E28FFBA9B20D69D1 CRC64;
     MSPLNAALFG MLIAILEKPE VIRSNPMDMC EYWTLIDELD EHPECVQSTT TKSTTTSPSP
     PPTCSSSAAL VQCTQDPETC PQSGQACIRS DGKKCCQAVT RGIPVSEINA KPGSCPTPLG
     ISVLHETAVG CWLDSGCPGI QKCCIEPNPT SNSATRICRD PVGVRSTSIC NLPLAVGTCT
     ATSLRFYYDS SSGNCKKFHY SGCGGNANNF QSLASCQATC AASGVMGAPL CPAESNIGLN
     CFIKHTDACT TDSDCLGREN NLQPSCCQTS CGHKICYLF
//