ID A0A0B4REX7_9BACL Unreviewed; 708 AA.
AC A0A0B4REX7;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=Plano_2535 {ECO:0000313|EMBL:AIY06500.1};
OS Planococcus sp. PAMC 21323.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Planococcus.
OX NCBI_TaxID=1526927 {ECO:0000313|EMBL:AIY06500.1, ECO:0000313|Proteomes:UP000031496};
RN [1] {ECO:0000313|EMBL:AIY06500.1, ECO:0000313|Proteomes:UP000031496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 21323 {ECO:0000313|EMBL:AIY06500.1,
RC ECO:0000313|Proteomes:UP000031496};
RA Jung J.-H., Joe M.-H., Cho Y.-J., Lee S.G., Han S.J., Lim S., Choi J.-i.;
RT "Complete genome sequence of Planococcus sp. PAMC21323 isolated from the
RT Antarctica.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
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DR EMBL; CP009129; AIY06500.1; -; Genomic_DNA.
DR RefSeq; WP_038704843.1; NZ_CP009129.1.
DR AlphaFoldDB; A0A0B4REX7; -.
DR STRING; 1526927.Plano_2535; -.
DR KEGG; pln:Plano_2535; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_004585_6_1_9; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000031496; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000031496}.
FT DOMAIN 14..294
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 295..558
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 35..42
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 708 AA; 82447 MW; 2D06359597203205 CRC64;
MSQFFERKKQ ELGVQLNKIQ RKAVERTEGP LLLLACPGSG KTTTMIMRIG YLIEEKGVFP
SRIKAITFSK ASANDMLERY KRFFPTLQPI DFSTIHSLAF QITRDYFSGS RYLMIEGNET
NGLHKKKLLR EMYRTENDEP ITDDQLEELI SFISFVKNKM LPRKQWAKLK EPFPGAIEIL
KTYEAFKENY DVRLVDFDDM LSLAYEALEK DKSLLAKYQG RWDYVMTDES QDTSQIQHAI
VEKLVARHQN LCVVADDDQS IYTWRAAEPT YLLKFRTVYP NAYIMKMERN YRSSQNIVHT
ANAFIKTNKK RHDKNMFTKQ GEGDPIVLKR LSSEDAQFKY VLKELKELTD YGDVAILYRN
NSSSTLLMSE LERLGIPFYM KDSDNRFFSH WIVEDMLNFM RFSLKPERID IYSKVASKTN
AYWSSSQLKM LSRMKPTGKH AFDDINLTIT LKDYQLKILA EQKKWFEALN NMKPLKVIRT
IRGEMGYDQM LASRAEKFGM KMTYLAQILT TLEQIAEPLD SMTAFAKRLK QLEQVTQQAK
KEKTDDMLTL STFHSSKGLE FERVYMIDLV EGVIPTEDDA ETPDLLEEAR RLFYVGMTRA
KTHLELVSHG NESRFVGEVR KLIVPEKRLA TTQSDKAKTP IKVKVPDNPN AIHTEEVLRE
GVRVRHRVFG AGKIVERDKD RISIQFAKER KDLMIDICIS YKLLETIE
//
