GenomeNet

Database: UniProt
Entry: A0A0B4XV37_9PROT
LinkDB: A0A0B4XV37_9PROT
Original site: A0A0B4XV37_9PROT 
ID   A0A0B4XV37_9PROT        Unreviewed;       526 AA.
AC   A0A0B4XV37;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   25-OCT-2017, entry version 21.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AJD50127.1};
GN   ORFNames=TH3_00005 {ECO:0000313|EMBL:AJD50127.1};
OS   Thalassospira xiamenensis M-5 = DSM 17429.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Thalassospira.
OX   NCBI_TaxID=1123366 {ECO:0000313|EMBL:AJD50127.1, ECO:0000313|Proteomes:UP000007127};
RN   [1] {ECO:0000313|EMBL:AJD50127.1, ECO:0000313|Proteomes:UP000007127}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M-5 {ECO:0000313|EMBL:AJD50127.1};
RX   PubMed=23209216; DOI=10.1128/JB.01904-12;
RA   Lai Q., Shao Z.;
RT   "Genome sequence of Thalassospira xiamenensis type strain M-5.";
RL   J. Bacteriol. 194:6957-6957(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP004388; AJD50127.1; -; Genomic_DNA.
DR   EnsemblBacteria; AJD50127; AJD50127; TH3_00005.
DR   KEGG; txi:TH3_00005; -.
DR   KO; K02313; -.
DR   Proteomes; UP000007127; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007127};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007127}.
FT   NP_BIND     231    238       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   526 AA;  58496 MW;  CC818F7AFE5A27E3 CRC64;
     MQHAVRGTQS ALGESNGGIP GDQQAALDDH AKATWQVVRE KLRSEFGATA YRYWLDPVAL
     IAVEAGVARL GAPTRAMRDW VTQHYLDRIQ SFWHSEDENI HFVEIVVVQP ANGNGQKNAS
     SSTTSNSAAQ SANSSARGRI SDDVARLDKA ANEVTGAEGS GLSYAGNAKG LVSGGRKAIG
     TMSDDGISAA LDPRYTFDNF VIGKPNEFAY AAARRLAEAE SVPFNPLFLY GGVGLGKTHL
     MHAIAWHIRR TQPHRTVIYL SAEKFMYRFI RALRDKNTVD FKDQFRSVDV LMVDDVQFIS
     GKDSTQEEFF HTFNALVDQG RQIIVSADKS PSDLEDIEER LRSRLGSGLV ADIHATTYEL
     RLGILESKAE RQNIELPQRV MEFLAHKITA NVRELEGALN RVIAHAQLVG REISLDMVQD
     VLHDVLRASE RRVSIEEIQK KVAEHFNIKV SDMHSARRAR AVARPRQVAM YLSKQLTTHS
     LPEIGRKFGG RDHTTVMHAV RKIEELHVSD PSLSEDIDLL RRMLEG
//
DBGET integrated database retrieval system