ID A0A0B4Y4Q1_9PROT Unreviewed; 1079 AA.
AC A0A0B4Y4Q1;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Fusaric acid resistance protein {ECO:0000313|EMBL:AJD53643.1};
GN ORFNames=TH3_17705 {ECO:0000313|EMBL:AJD53643.1};
OS Thalassospira xiamenensis M-5 = DSM 17429.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Thalassospiraceae; Thalassospira.
OX NCBI_TaxID=1123366 {ECO:0000313|EMBL:AJD53643.1, ECO:0000313|Proteomes:UP000007127};
RN [1] {ECO:0000313|EMBL:AJD53643.1, ECO:0000313|Proteomes:UP000007127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M-5 {ECO:0000313|EMBL:AJD53643.1,
RC ECO:0000313|Proteomes:UP000007127};
RX PubMed=23209216; DOI=10.1128/JB.01904-12;
RA Lai Q., Shao Z.;
RT "Genome sequence of Thalassospira xiamenensis type strain M-5.";
RL J. Bacteriol. 194:6957-6957(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP004388; AJD53643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B4Y4Q1; -.
DR STRING; 1123366.TH3_17705; -.
DR KEGG; txi:TH3_17705; -.
DR eggNOG; COG1289; Bacteria.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_010100_0_0_5; -.
DR Proteomes; UP000007127; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30367:SF12; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF04632; FUSC; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 770..792
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 810..857
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
SQ SEQUENCE 1079 AA; 118595 MW; 41880032E6AA0A38 CRC64;
MTQAIKIGIN FFCSPTLKID ANAILFSAKT FIAAMLAYYI SLRIGLPRPF WAIITVYIVS
QTSAGASLSR GVYRFAGTFI GAIATVAIVP NFANEPILCS LILSGWIGLC LFFSLLDRTP
RAYAFVLAGY TASLIGFPSV LDPGAVFDIA SLRVQEISIG ILCAVLIHRY VLPKRMTGLF
TGKLATTMQN AHQLAKDALN GTPEENRSDR KQLSLDLLTL QDLATHLPYD PAPVIPHRRI
LRLIHDRLAR LLLLTTEIEE RIHFLRHDGD FAPAELTRLI DDVRTWCTLA DIADESDATF
DLIAHARTVQ KQLAKEKASS VDLVGANLAG HLAEMIGLLH DCKQLKFSAT LINPLRNTRS
LHGPKHARGY VYHRDPQMAA RAALGAITGI LCGCAFWIWS GWTEGGTAVS VLGVCCTLFG
NFDTPVPFVV KYTIGTLYGI AFSLFYSFFI LPQVTDFAVL VAVLAPAFLL AGSLQARLPT
MMTALGIALT IPILSGLGTN YSGDFAASLN ISIAVLVAVN FGALSMSMFQ TVRADTAIKR
LLDLSRRDIG RRALGHAPNE ARWISLMIDR TALLQPKLRA SGKAYSSVLD DTLHHLRIGH
VAGRLHKMIP LLPFEARAPI KDLLLATANY VNARKPTKNH DPVPLNQHIA TVMAISTQGP
KKNRTQIRDL LIDLCFALLW VQRPFRRREN PYHDPGCQFL GSSDSRLGGS RRYGTGRNHR
NHTLAVRYPL IPHLYLQTAH RARPLYHHLR SAHAIPAIKR IFTVKTVISL VGRYIVTLCL
VAASAFVAFK AWSHYDKTLW TRDARVGVDV VQIAPEVSGT IRSVSVADNQ YVKQGDVLYQ
IEPERLELAV ALAKADVEAK QQDMIVRQAT ARRQRQLKDF ASREAIQQAN GAAAVASAAY
QSAQASLDLA KLNLARSTIR STVDGYVTNL KLRPGDYATA GITKISVIDA SSFWVTGYFE
ETKIGRIHIG APISIQLMGF DQPAFGHVES IGRGIENSND TPGHLGLPNV ATTFSWVRLA
QRIPVRIKID KIPASIELVA GMTATVQVMR QDRATNTDNH ASSAYPDLDG LYRLKHSEY
//
