ID A0A0B5DNU2_9ACTN Unreviewed; 515 AA.
AC A0A0B5DNU2;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=3-(3-hydroxy-phenyl)propionate hydroxylase {ECO:0000313|EMBL:MBB4794342.1};
DE EC=1.14.13.127 {ECO:0000313|EMBL:MBB4794342.1};
DE SubName: Full=Bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase {ECO:0000313|EMBL:QEV41476.1};
DE SubName: Full=Monooxygenase {ECO:0000313|EMBL:AJE42970.1};
GN ORFNames=BJY54_004954 {ECO:0000313|EMBL:MBB4794342.1}, CP978_25560
GN {ECO:0000313|EMBL:QEV41476.1}, SNOD_25240
GN {ECO:0000313|EMBL:AJE42970.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE42970.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE42970.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE42970.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
RN [3] {ECO:0000313|EMBL:QEV41476.1, ECO:0000313|Proteomes:UP000325763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:QEV41476.1,
RC ECO:0000313|Proteomes:UP000325763};
RA Lee N., Cho B.-K.;
RT "Streptomyces genome completion.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB4794342.1, ECO:0000313|Proteomes:UP000544950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40109 {ECO:0000313|EMBL:MBB4794342.1,
RC ECO:0000313|Proteomes:UP000544950};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009313; AJE42970.1; -; Genomic_DNA.
DR EMBL; JACHMR010000001; MBB4794342.1; -; Genomic_DNA.
DR EMBL; CP023747; QEV41476.1; -; Genomic_DNA.
DR RefSeq; WP_043444669.1; NZ_JACHMR010000001.1.
DR STRING; 40318.SNOD_25240; -.
DR KEGG; snq:CP978_25560; -.
DR HOGENOM; CLU_009665_20_2_11; -.
DR OrthoDB; 8670884at2; -.
DR Proteomes; UP000031526; Chromosome.
DR Proteomes; UP000325763; Chromosome.
DR Proteomes; UP000544950; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43476; 3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE; 1.
DR PANTHER; PTHR43476:SF3; FAD_BINDING_3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Monooxygenase {ECO:0000313|EMBL:AJE42970.1};
KW Oxidoreductase {ECO:0000313|EMBL:MBB4794342.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031526}.
FT DOMAIN 6..342
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 515 AA; 57315 MW; 88C33BDA3DCD9C0A CRC64;
MPQNFDADVA VIGYGPTGVV GALTLAQQGA RVIAFERDKE IYPRARAVTV NDWTMRIFQS
LGIGERIEKV IDPQRALRWV TYDGHEVMRI EHPPSALGAR ARFYNIYQPV MESELRSCAQ
DRQDLISVRY GAEVTEIEQD GSGVTVTTTD TATGEVRRYR TRYAIAADGG SSRTRQRLGI
QLLGDTNEVS WVVIDCRVKR WWPDRDFLTF WTDQERPVVD IALSAGNHRW EIPLKPHETE
ADFPTATEVW PLLKALGVSE DDVEIHQHAF YRHHVRMART WRSGRVFLAG DAAHLMPPWA
GAGMQTGMRD AHNLGWKLGR VLAGKLPESW LDTYEAERRP NAAFYTGLAV QLGRVIKQEI
SDEERAALSA PPPDGLVTPF EPPLIASPVL EAGWLRGPLG DASIVGRMVP QPVVGDTVGR
MAPLDELLGD TFVLLGDDID PSTLLTEEER RQWDALGARY RAVRPQNAYT QGPDELVDLD
GVLGSWLRRY GVRAVALRPD RFVAAADTSG LAVPA
//
