ID A0A0B5DPT5_9ACTN Unreviewed; 1003 AA.
AC A0A0B5DPT5;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=ATP-binding protein {ECO:0000313|EMBL:AJE42486.1};
DE SubName: Full=TIR domain-containing protein {ECO:0000313|EMBL:QEV40992.1};
DE SubName: Full=Tetratricopeptide (TPR) repeat protein {ECO:0000313|EMBL:MBB4793798.1};
GN ORFNames=BJY54_004410 {ECO:0000313|EMBL:MBB4793798.1}, CP978_22750
GN {ECO:0000313|EMBL:QEV40992.1}, SNOD_22435
GN {ECO:0000313|EMBL:AJE42486.1};
OS Streptomyces nodosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=40318 {ECO:0000313|EMBL:AJE42486.1, ECO:0000313|Proteomes:UP000031526};
RN [1] {ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|Proteomes:UP000031526};
RA Sweeney P., Stephens N., Murphy C., Caffrey P.;
RT "Sequence of the Streptomyces nodosus genome.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJE42486.1, ECO:0000313|Proteomes:UP000031526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:AJE42486.1,
RC ECO:0000313|Proteomes:UP000031526};
RX PubMed=26497174;
RA Sweeney P., Murphy C.D., Caffrey P.;
RT "Exploiting the genome sequence of Streptomyces nodosus for enhanced
RT antibiotic production.";
RL Appl. Microbiol. Biotechnol. 100:1285-1295(2016).
RN [3] {ECO:0000313|EMBL:QEV40992.1, ECO:0000313|Proteomes:UP000325763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14899 {ECO:0000313|EMBL:QEV40992.1,
RC ECO:0000313|Proteomes:UP000325763};
RA Lee N., Cho B.-K.;
RT "Streptomyces genome completion.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB4793798.1, ECO:0000313|Proteomes:UP000544950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40109 {ECO:0000313|EMBL:MBB4793798.1,
RC ECO:0000313|Proteomes:UP000544950};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009313; AJE42486.1; -; Genomic_DNA.
DR EMBL; JACHMR010000001; MBB4793798.1; -; Genomic_DNA.
DR EMBL; CP023747; QEV40992.1; -; Genomic_DNA.
DR RefSeq; WP_043443816.1; NZ_JACHMR010000001.1.
DR STRING; 40318.SNOD_22435; -.
DR KEGG; snq:CP978_22750; -.
DR HOGENOM; CLU_000288_125_8_11; -.
DR OrthoDB; 580767at2; -.
DR Proteomes; UP000031526; Chromosome.
DR Proteomes; UP000325763; Chromosome.
DR Proteomes; UP000544950; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; NF040586; FxSxx_TPR; 1.
DR PANTHER; PTHR46082:SF6; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF13374; TPR_10; 3.
DR Pfam; PF13424; TPR_12; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:AJE42486.1};
KW Nucleotide-binding {ECO:0000313|EMBL:AJE42486.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031526}.
FT DOMAIN 20..141
FT /note="TIR"
FT /evidence="ECO:0000259|Pfam:PF13676"
FT DOMAIN 195..320
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1003 AA; 111915 MW; 03243AA35A65DC43 CRC64;
MSGARTPVGP TEKGAGRQTV TISFAGFNRA WAAWIGDRLE RRGLRVVYLR WDSPSGIPLE
DLLRDLKLAE GRILIVVSEW YFQLGPRTHE EWNAALRAVV GPDPSRFAAV SVTTSAVPAA
SAVLAAVDLT NMGAEEAERR LLDRLDLPAQ PQSEPAHDAR RGPRFPAAMP EVWGGVPRRN
TRFTGRETLL NDAYHLLQGA EPGAGVLTLH GMSGVGKTQT AAEYVYRFGS EYDVVWWVNA
EKRVGYRRLL AELAPKLGLA TGQEYGERLR AVRDSLRRGD PYARWLLVLD GADEPDQIWD
LVPTGPGHVL ITSRNPEWTE HNSRLLEVPV YQRYESVAFI RRRAPRLTEA EADQLAEALE
DLPLLLDQTA GWLNDSDLSV DDYIGLLEGG IDQDVVKVSA DFPLAFQTAW SILLNKLRET
VPESVDLLRL CTFFAPGFVP VRLLKEMPHD ELPEQVAGLL NDPLLWNKAI NQLRQYSVVR
LESHDTTADD PSATGESLYL HRMVHQIVGE DMPAEDREEF ITVVRQALAA ADPRRPTDPD
LWPAYAEIVP HLKYADVLNS TDPAIQRLVF NCLRYMYFSG EYRAGIKLGE RALATWRALL
GEAHPRIWEL TYHYANLLRA VGDYARTEAI ERVAVDHLRQ ERGPQDLEHL RASSGLAADL
RGLGRYDEAF QVSQWTLAAY RELLGEQDSR TLNAQNNLGA TLVLLGRYEE ALESDRRTLE
ARRQLLRARH PWTLYSETSY AIDLRLLGRY GEAESVQTKN VREQLRVLGA KNPYTLKARH
NLACCHYRSG DREQAGKLFA DVLEQSERVL GETNPDTLRY AVSQSCFTRE HGDIDQAREL
SEATIARYEV MLAEGHPFVA GARANHALIL RGVGERDHAH VLVEQALTDM TAAVGPDHPW
TLGCAVNASA LRSLVGDPES AAELSGTTAA RAAEVLGRTH PLTLSARIAR AADLRSLRDG
RQAEKLEQEA LSDLAATLGP QHVHTISARA RSRPFWDFEP QTT
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