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Database: UniProt
Entry: A0A0B5FAV0_9DELT
LinkDB: A0A0B5FAV0_9DELT
Original site: A0A0B5FAV0_9DELT 
ID   A0A0B5FAV0_9DELT        Unreviewed;       455 AA.
AC   A0A0B5FAV0;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   25-OCT-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=GSUB_00005 {ECO:0000313|EMBL:AJF05292.1};
OS   Geoalkalibacter subterraneus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geoalkalibacter.
OX   NCBI_TaxID=483547 {ECO:0000313|EMBL:AJF05292.1, ECO:0000313|Proteomes:UP000035036};
RN   [1] {ECO:0000313|EMBL:AJF05292.1, ECO:0000313|Proteomes:UP000035036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red1 {ECO:0000313|EMBL:AJF05292.1,
RC   ECO:0000313|Proteomes:UP000035036};
RX   PubMed=25767222;
RA   Badalamenti J.P., Krajmalnik-Brown R., Torres C.I., Bond D.R.;
RT   "Genomes of Geoalkalibacter ferrihydriticus Z-0531T and
RT   Geoalkalibacter subterraneus Red1T, Two Haloalkaliphilic Metal-
RT   Reducing Deltaproteobacteria.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP010311; AJF05292.1; -; Genomic_DNA.
DR   RefSeq; WP_040198527.1; NZ_CP010311.1.
DR   EnsemblBacteria; AJF05292; AJF05292; GSUB_00005.
DR   KEGG; gsb:GSUB_00005; -.
DR   KO; K02313; -.
DR   Proteomes; UP000035036; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035036};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035036}.
FT   DOMAIN      152    280       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      363    432       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     160    167       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   455 AA;  52134 MW;  A0BA1B236771AE3D CRC64;
     MDTLWRETLE QLEQKLSPQL FSTWIKPIEF IRVEKSNVFL RVPNRFFLDW IRDNYVRKIE
     ETLADVGAVE YKVEFEVSSR PRQQENSPAK NSEQTKKESF TPAPQAASAK PAAENWNTNL
     NPKYIFTDFV SGSSNQFAHA AAMAVANNPA TTYNPLFIYG GVGLGKTHLV NAIGNAILKK
     NSSMRVCYYT SEKFMNELIN SLRYARMDEF RNKFRSMDVL LIDDVQFIAG KERTQEEFFH
     TFNALYESHK QIVVTSDKFP KEIPGLEERL RSRFEWGLIA DIQPPDVETK QAILKMKAEK
     NRINLPEEVI QFLSNSITSN VRELEGFLIR LGAYASLTST PITLDLAREV LKDILVEKNK
     EITVEEIQKV VAQHFSLKVA DLKSPKRLKA LVLPRQIAMY LSRQLTSQSF PEIGDKFGGK
     DHSTIIHAIK KVEKLMEDDF QLRTTVGNLK NALSR
//
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