ID A0A0B7MX32_9FUNG Unreviewed; 836 AA.
AC A0A0B7MX32;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=RhoGAP-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=PARPA_03228.1 scaffold 7241 {ECO:0000313|EMBL:CEP09677.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP09677.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP09677.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP09677.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN722188; CEP09677.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7MX32; -.
DR STRING; 35722.A0A0B7MX32; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00132; LIM; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Reference proteome {ECO:0000313|Proteomes:UP000054107};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 9..73
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 540..588
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 639..828
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 76..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 216..264
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 85..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 92391 MW; 7E0B9AFDA97AA545 CRC64;
MVVNEIIVPT CQGCCELIEE GAVVAFGDSL FHVKCFICAK CGECVDNKIN LLLLDDGRPG
IYCTVCNKTR KADRQTKKSK ASDASQSSKE SLCQDQQLPQ PSCQQNQARP ISISPKLPTP
DRSRSNSPVQ KAIMEVNSSC NSVLLEDFTF SFFENDSNEL NNLSNTLGAN LTLSDDKYTP
QYRIKRASEI LQTSLRTSSL SKTSNEPSPS AQNDELIETR SRLKELEANY KVLQDASQQA
LNEITQLKDD LEQESAIKKQ QELTIVSLMS KSNTLLSRKE VDKLAYVRIE LERACKELIH
YRDKIATTLD EQVSNTTVFP NYQKSLKMQI KSLIQERNLL KSQTKDLATS RDEVIHEMVL
LNTKIAELAT MNNDLSRRVI AKEEATLTAS PAMPLSNSPP LSPSRSSDAL SRIPPASAQH
LRKPSNASST VLNASSKKSF ISDQTPTLFR LKKKGSTMFG KLGTVSATPK PSKLDIPSSG
LLSSSSSSIF RATSKTIYNN PSYSSSLQSI NYQDSSALGK SSSKSFTNTS ISLSRAVHES
HSFQPTFFLK PVKCGSCGDK IWSRSEYRCD GCGLSSHSRC LSKVSQQCTV ANTSSSLDLG
SSSSFENASS PKTSSSDIEG KTLPQQLTKS TTDCSIFGSC LSEHVKTENR TVPLIVEECI
KEVEKRGLDC EGIYRKSGGA AQIRAIQLAF EKGEDINLSD EVQYNDVCAI TSVLKQFFRE
LSNPLLTFEL YDQFIQASAM DHGEEKTKAF SNVLQQLPMA HIDTLEMLLR HLVDVYKQSD
VNRMSVKNLA MVFAPTLMRH SDTSKDFLDI SYKNATIEYL LLHKSELFSA PSPSTS
//
