ID A0A0B7N4F1_9FUNG Unreviewed; 1019 AA.
AC A0A0B7N4F1;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Ras-GEF domain-containing protein {ECO:0000259|PROSITE:PS50009};
GN Name=PARPA_03993.1 scaffold 10876 {ECO:0000313|EMBL:CEP10323.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP10323.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP10323.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP10323.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN723807; CEP10323.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7N4F1; -.
DR STRING; 35722.A0A0B7N4F1; -.
DR OrthoDB; 1387014at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF368; RAS-GEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000054107}.
FT DOMAIN 541..794
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 266..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 760..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 817..873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 927..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..288
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..908
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 939..965
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1019
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1019 AA; 113775 MW; 58ABD713812DD3A2 CRC64;
MTSLAGCQYL RRAPSVAREM ETEERDELEI VQCEQSGSQE VVTSKEATIS VSRSNGKIEC
PVVGCLKTFT NSVVFRDHCN TIHRGTVKTI GYEEESDLLR DSKRVKKNED SALFTMVHGS
QHALQMQSES KAFHTMAAID CEPVAMHFSH EKMSDTSSVH CLLHRENMIK TLKKAPISLN
LQFSEPLHCT LQVHNNDNQI KRTDPGTVTN VVPFIKNAVD TSFLPDLLEN NGPPDEYNES
IALLRSSLDQ LEKIAIHRLP GAITSSLQKT RSPPPPVPPK PSTIHHKPMV PPKPKKIIPK
VEDAKVIQQQ KRARGNSVSF AEDSKLLRMT IIENDEEEDK GSISMMDAKS TDEDEEVEVG
FETKTATSSS ASSTSSPPSP PAKRPATVNF DHHHYPINDM KPCEPRQRSQ SWVVHSDASS
QRDSIDVLLE TVVDPRNLVP AQTNAGDSIS LPGSSETTSS QTQYVPNIPA PPLLATHRRL
QQRLNELETD LERTAAMTTS DGMLLLRSER SHQARCARQT LEKVRTLYMS AMTIPSILQF
SPQLIAYQLT LIESSIFRAI PPEALLSHST RTPHKKIVAS TDFFNFVTRS IEHSILLPQE
ASRRAEIIHR WIKIATKLLA IHNYQTLKAV ISALGTPPIQ RLRRTWECIP KKRSARLELL
NTLMSETDNY RKYREHMSLE GNKRLWTKPV VPFLGVYIHD VTYLYAAAKG NQHDCRVQDV
LNCVKLFQRA PIYPQHPPAA FVSVQKRHLF RPMLSDALHF GSSSKKSNSK TPTAAAALMG
EEQGQETELE LEQQLIIQYL LMRPWVSEKV IDALSNLREP PKSRSASSPT SSRYSSDSTI
NLSITTSLTT NHGGGSTPKT LSPTTTTASN NSSSILGNAS SFIRFSSNSI SSHHPQHHSD
EGPPDEENKR SIVGGFWPFR KSIDASRNSI SADESPTWNQ EFNDDDEDDD DDDDDEVEEE
EVKEQDIQAL IEQASKHGLL NMRKRPSTVA DPSSRGHNRS ISLPSKSIQV SELYHSSGV
//
