ID A0A0B7NPE4_9FUNG Unreviewed; 1035 AA.
AC A0A0B7NPE4;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Dynamin-binding protein {ECO:0000256|ARBA:ARBA00018186};
DE AltName: Full=Scaffold protein Tuba {ECO:0000256|ARBA:ARBA00032587};
GN Name=PARPA_11534.1 scaffold 44469 {ECO:0000313|EMBL:CEP17238.1};
OS Parasitella parasitica.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Parasitella.
OX NCBI_TaxID=35722 {ECO:0000313|EMBL:CEP17238.1, ECO:0000313|Proteomes:UP000054107};
RN [1] {ECO:0000313|EMBL:CEP17238.1, ECO:0000313|Proteomes:UP000054107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 412.66 {ECO:0000313|EMBL:CEP17238.1,
RC ECO:0000313|Proteomes:UP000054107};
RA Ellenberger Sabrina;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
CC Golgi apparatus, Golgi stack {ECO:0000256|ARBA:ARBA00004348}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LN733661; CEP17238.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0B7NPE4; -.
DR STRING; 35722.A0A0B7NPE4; -.
DR OrthoDB; 1358837at2759; -.
DR Proteomes; UP000054107; Unassembled WGS sequence.
DR GO; GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd17352; MFS_MCT_SLC16; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054107};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 117..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..503
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 505..614
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 973..1035
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 597..624
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1035 AA; 115286 MW; 7F060FDA86655B9F CRC64;
MSKPTDQNQS FGGKSQNSAC DDEEEDMKTV QCTEDASLPL PSSSQQQQQQ YEYPAVLESA
PFPALGSLIE ITQTLSKVRS NQSQQNEKSI LGELDQNEQL AFKQVPYHTD GLRNPGWLTV
LSCFFVNFFV FGTTFSWGNY QKLYIDQVYA GKTNLLKIAF VGTSASALML ALGMFITPVI
QKIGFRGTML IGTIVSPLAL ILASFATELW HIYLSQGILF GIGAAFVFSP SVTLPSQWFT
AKRALATGIA VSGSGIGGVC LSPMTQRLIV SMGYRNTLRV QGTFGFGLLC ISTALATSRY
RPPPSLNSKN RWYHIYDSSL ISRRLVLLLG FSFFVPFGYV APFFLAPQYV QSIGLDASTG
AAMISVMSAA NAVCRITLGY LADRSGRFNT MFSCTFLAGL FTMLIWQFSA NYGTFVAYCV
LYGLTAGGFV SLLPVVTADI VGVENIQRGL GMAYMTTVIG NLLGTPIIGL LFDSFGWTAA
IQFAGSMSIV SAIFMLVLRM ILSRGKLFVK IMREIDSIYS EYCKRQEDAV LRLQELELLP
QLQAFLNGCK EKIQGKTTSW DLGSLLIKPV QRVLKYPLLL RELHSLTPPT HVDHDDLSAA
VKEIQEVADN INEIKRRKDI VEKIVGDKKK TDINVGIKSM QRQKKKWTLT FCVLHGINKR
FTRKAQKFKQ VTGLAGEPTH DLVFEALLLK FEEQQDLVRQ LAREVQGWVR HVKIGFENLQ
QLACSMESLY GSWGGVRVKR LNEISDFSRM ASYMSSNLSR ELDNDVRGFV YSRIDDFLRV
FENPAQVIHK RALKMIDYDR VRDMKLKGDV PDKALQESAD AYVSINGQLV DELPKFFSLT
AKYFDILTGG LALVQVKFFG LMQKEWIKLI EQNLGVKAAK SFEAIIANHM DELDKVEDIA
SKIAVLQKCS SSAKISSSNS SLSLNQGSGN LYSPRIAFGN FSPQLLAAST VTAPAPVAGH
LIDLEQDGPV STPQDFNCIV LYDFEMDEED RLNVKRGTIL RVSQDEDYLD QDWWFATTTD
DFKSGWVPIN YCKKL
//
