ID   A0A0B8NHQ6_9NOCA        Unreviewed;       573 AA.
AC   A0A0B8NHQ6;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:GAM47678.1};
GN   ORFNames=NS07_v2contig00055-0032 {ECO:0000313|EMBL:GAM47678.1};
OS   Nocardia seriolae.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=37332 {ECO:0000313|EMBL:GAM47678.1, ECO:0000313|Proteomes:UP000019401};
RN   [1] {ECO:0000313|EMBL:GAM47678.1, ECO:0000313|Proteomes:UP000019401}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N-2927 {ECO:0000313|EMBL:GAM47678.1,
RC   ECO:0000313|Proteomes:UP000019401};
RA   Imajoh M., Fukumoto Y., Yamane J., Sukeda M., Shimizu M., Ohnishi K.,
RA   Oshima S.;
RT   "Draft Genome Sequence of Nocardia seriolae Strain N-2927 (NBRC 110360),
RT   Isolated as the Causal Agent of Nocardiosis of Yellowtail (Seriola
RT   quinqueradiata) in Kochi Prefecture, Japan.";
RL   Genome Announc. 3:e00082-15(2015).
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAM47678.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BAWD02000055; GAM47678.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0B8NHQ6; -.
DR   STRING; 37332.NS506_07065; -.
DR   Proteomes; UP000019401; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR007887; MecA_N.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF05223; MecA_N; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019401}.
FT   DOMAIN          17..119
FT                   /note="NTF2-like N-terminal transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF05223"
FT   DOMAIN          299..556
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   573 AA;  58216 MW;  252F359F06F46203 CRC64;
     MTATACSSDP TSGLSKTVDG FADALNRDDV QAAATATSDP ATAATTLGAL YDNLGKQVRF
     AASKVEKTDN GGTFTLNATW KLGTDGKDEW TYTTTGRADK SGGDWKIQWD PATIAPGLNI
     GPLTYGIAYP NPAKVLDGAG GDLLTQQVVT LVNVAPGADT AAVAAALRPV VPDITAASLQ
     SELAAAQGKP ITAVTLRESD YATVQPALAN LANVTTAQQT RLLAVDKSLA SPTFSGLSEL
     WQQQADAAAG WAVRAQGGGG TQRVGGPDPK PVSDIRTTLD LGLQRAAQAA LAPITTPAAI
     VAIQPSTGDV LAMAQNAAGD AQGPIGLTGL YPPGSTFKTV TVSAALQAGE VTPDSMVACP
     GKENIEGRTI PNDNNFDLGQ VPLHTAFAKS CNTTMGRLAV QLAPDGLTNA AAQLGLGIDY
     VTPGLTTVTG KVPTADTPAL RVEEGIGQGK VTASPFGMAL VAAALAQGSV KPPTVVQGQP
     GKPDRQPPAL PAGIADQVKS MMRETITGGT ATALRDIPGL LGKTGTAEYI DDKHAHGWFV
     GIDGDLAFAV FISDAGSSEP AVQAAGRMLR APR
//