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Database: UniProt
Entry: A0A0B8PXT3_9VIBR
LinkDB: A0A0B8PXT3_9VIBR
Original site: A0A0B8PXT3_9VIBR 
ID   A0A0B8PXT3_9VIBR        Unreviewed;       457 AA.
AC   A0A0B8PXT3;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   25-OCT-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=JCM19236_4435 {ECO:0000313|EMBL:GAM71101.1};
OS   Vibrio sp. JCM 19236.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=1481926 {ECO:0000313|EMBL:GAM71101.1, ECO:0000313|Proteomes:UP000031680};
RN   [1] {ECO:0000313|EMBL:GAM71101.1, ECO:0000313|Proteomes:UP000031680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM19236 {ECO:0000313|EMBL:GAM71101.1,
RC   ECO:0000313|Proteomes:UP000031680};
RA   Sawabe T., Meirelles P., Feng G., Sayaka M., Hattori M., Ohkuma M.;
RT   "Vibrio sp. C94 JCM 19236 whole genome shotgun sequence.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GAM71101.1, ECO:0000313|Proteomes:UP000031680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM19236 {ECO:0000313|EMBL:GAM71101.1,
RC   ECO:0000313|Proteomes:UP000031680};
RG   NBRP consortium;
RA   Sawabe T., Meirelles P., Feng G., Sayaka M., Hattori M., Ohkuma M.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAM71101.1}.
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DR   EMBL; BBSB01000021; GAM71101.1; -; Genomic_DNA.
DR   EnsemblBacteria; GAM71101; GAM71101; JCM19236_4435.
DR   Proteomes; UP000031680; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031680};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031680}.
FT   DOMAIN      154    367       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      365    434       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     162    169       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   457 AA;  51909 MW;  EA0EE8D4F4577E7B CRC64;
     MQQLQEELPA TEFSMWVRPL QAELSDNTLT LFAPNRFVLD WVRDKYINSI NRHLQQFCGN
     DIPSLRFEVG SKPVSSPPAP KKSAADVAAE SSAPAQLARR QQIHKTWDKE TEVADIAYRS
     NVNPKHRFNN FVEGKSNQLG LAAARQVSDN PGAAYNPLFL YGGTGLGKTH LLHAVGNAIV
     DNKPNAKIVY MHSERFVQDM VKALQNNAIE EFKRYYRSVD ALLIDDIQFF AHKERSQEEF
     FHTFNALLEG NQQIILTSDR YPKEITGVED RLKSRFGWGL TVAIEPPELE TRVAILMKKA
     EDHQIHLADE VAFFIAKRLR SNVRELEGAL NRVIANANFT GRPITIDFVR EALRDLLALQ
     EKLVTIDNIQ KTVAEYYKIK VADLLSKRRS RSVARPRQLA MALAKELTNH SLPEIGDAFG
     GRDHTTVLHA CRKIDQLREE SHDIKEDYSN LIRTLSS
//
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