ID A0A0B8UMC3_PISSA Unreviewed; 109 AA.
AC A0A0B8UMC3;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Glutaredoxin {ECO:0000256|PIRNR:PIRNR005894};
GN Name=grxD {ECO:0000313|EMBL:QGO06784.1};
GN ORFNames=AB894_03470 {ECO:0000313|EMBL:KLV36364.1}, AVI55_09795
GN {ECO:0000313|EMBL:APS67297.1}, Psal009_02712
GN {ECO:0000313|EMBL:QGO06784.1}, Psal159_00772
GN {ECO:0000313|EMBL:QGP25047.1};
OS Piscirickettsia salmonis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Piscirickettsia.
OX NCBI_TaxID=1238 {ECO:0000313|EMBL:APS67297.1, ECO:0000313|Proteomes:UP000185519};
RN [1] {ECO:0000313|EMBL:KLV36364.1, ECO:0000313|Proteomes:UP000037680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LF-89 {ECO:0000313|EMBL:KLV36364.1,
RC ECO:0000313|Proteomes:UP000037680};
RA Bravo C., Machuca A., Martinez V.;
RT "Draft genome sequence of virulent Piscirickettsia salmonis isolate.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:APS67297.1, ECO:0000313|Proteomes:UP000185519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AY6297B {ECO:0000313|EMBL:APS67297.1,
RC ECO:0000313|Proteomes:UP000185519};
RA Bohle H., Henriquez P., Grothusen H., Navas E., Bustamante F., Bustos P.,
RA Mancilla M.;
RT "Genome sequencing identifies Piscirickettsia salmonis subsp. salmonis
RT subsp. nov. and Piscirickettsia salmonis subsp. salaris subsp. nov.,
RT isolated from Salmonids with Piscirickettsiosis.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QGO06784.1, ECO:0000313|Proteomes:UP000422232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Psal-009 {ECO:0000313|EMBL:QGO06784.1,
RC ECO:0000313|Proteomes:UP000422232};
RA Schober I., Bunk B., Sproer C., Carril G.P., Riedel T.,
RA Flores-Herrera P.A., Nourdin-Galindo G., Marshall S.H., Overmann J.;
RT "Complete genome sequencing of Piscirickettsia salmonis strain Psal-009.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QGP25047.1, ECO:0000313|Proteomes:UP000818417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Psal-159 {ECO:0000313|EMBL:QGP25047.1,
RC ECO:0000313|Proteomes:UP000818417};
RA Schober I., Bunk B., Sproer C., Carril G.P., Riedel T.,
RA Flores-Herrera P.A., Nourdin-Galindo G., Marshall S.H., Overmann J.;
RT "Complete genome sequencing of Piscirickettsia salmonis strain Psal-159.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutaredoxin family. Monothiol subfamily.
CC {ECO:0000256|ARBA:ARBA00009630, ECO:0000256|PIRNR:PIRNR005894}.
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DR EMBL; CP013791; APS67297.1; -; Genomic_DNA.
DR EMBL; LELB01000045; KLV36364.1; -; Genomic_DNA.
DR EMBL; CP038908; QGO06784.1; -; Genomic_DNA.
DR EMBL; CP039186; QGP25047.1; -; Genomic_DNA.
DR RefSeq; WP_017377041.1; NZ_PDFD01000177.1.
DR AlphaFoldDB; A0A0B8UMC3; -.
DR STRING; 1238.AWJ11_12675; -.
DR GeneID; 66740148; -.
DR OrthoDB; 9804115at2; -.
DR Proteomes; UP000037680; Unassembled WGS sequence.
DR Proteomes; UP000185519; Chromosome.
DR Proteomes; UP000422232; Chromosome.
DR Proteomes; UP000818417; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd03028; GRX_PICOT_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR033658; GRX_PICOT-like.
DR InterPro; IPR014434; Monothiol_GRX.
DR InterPro; IPR004480; Monothiol_GRX-rel.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; TIGR00365; Grx4 family monothiol glutaredoxin; 1.
DR PANTHER; PTHR10293; GLUTAREDOXIN FAMILY MEMBER; 1.
DR PANTHER; PTHR10293:SF72; MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC; 1.
DR Pfam; PF00462; Glutaredoxin; 1.
DR PIRSF; PIRSF005894; Monothiol_GRX; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 3: Inferred from homology;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714, ECO:0000256|PIRSR:PIRSR005894-2};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR005894-2};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|PIRSR:PIRSR005894-
KW 2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR005894-2}.
FT DOMAIN 17..81
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
FT BINDING 22
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
FT BINDING 30
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /ligand_note="ligand shared between dimeric partners"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-2"
FT BINDING 59
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
FT BINDING 71
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
FT BINDING 84..85
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
SQ SEQUENCE 109 AA; 11530 MW; 8F92CD93A6BCAF83 CRC64;
MENTVDMIKG QIADTAVLLY MKGSPQQPQC GFSAQAVQAL MACGVKFGYV DVLASPEVRA
TLPQVSSWPT FPQLFINGEL VGGSDIVAEL HQSGELQTML DAVKGASAE
//
