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Database: UniProt
Entry: A0A0C1FHN4_9SPHI
LinkDB: A0A0C1FHN4_9SPHI
Original site: A0A0C1FHN4_9SPHI 
ID   A0A0C1FHN4_9SPHI        Unreviewed;       476 AA.
AC   A0A0C1FHN4;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   25-OCT-2017, entry version 23.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=OC25_21915 {ECO:0000313|EMBL:KIA91293.1};
OS   Pedobacter kyungheensis.
OC   Bacteria; Bacteroidetes; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=1069985 {ECO:0000313|EMBL:KIA91293.1, ECO:0000313|Proteomes:UP000031246};
RN   [1] {ECO:0000313|EMBL:KIA91293.1, ECO:0000313|Proteomes:UP000031246}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KACC 16221 {ECO:0000313|EMBL:KIA91293.1,
RC   ECO:0000313|Proteomes:UP000031246};
RA   Anderson B.M., Newman J.D.;
RT   "Pedobacter Kyungheensis.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIA91293.1}.
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DR   EMBL; JSYN01000031; KIA91293.1; -; Genomic_DNA.
DR   RefSeq; WP_025145530.1; NZ_JSYN01000031.1.
DR   EnsemblBacteria; KIA91293; KIA91293; OC25_21915.
DR   Proteomes; UP000031246; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031246};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031246}.
FT   DOMAIN      172    302       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   476 AA;  53949 MW;  8879A5E7DF2C4F2B CRC64;
     MEKTCTEVWK NCLQIIKDNI PNQSFKTWFE PITALKLEGK VLTIQVPSLF FYEWLEEHYV
     GLLRKTVKKQ LGEDGRLEYN IVVDKSSNSG NPYTTNMPSN GNGAEAKVQS MPIPVSINKD
     IKNPFIIPGL KKLNVDPQLN SNYTFENYIE GDCNRLARSA GYAVAAKPGG TSFNPLMIYG
     GVGLGKTHLA QAIGNEIKRS MPDKLVIYVS CEKFCQQFVD SLKNNTINDF VNFYQAMDVI
     IMDDVHNFAG KEKTQDIFFH IFNHLHQSGK QVILTSDKAP KDLAGLEERL LSRFKWGLSA
     DLQIPDLETR IAILRKKMYA DGIELPGEVV EYVAHNIDNN VRELEGAMVS LLAQATLNKK
     EIDLALAKQM LKNFIKNTSK EISMEYIQKL VCEYFEVPVD MVKSQTRKRE IVQARQISMY
     LSKSHTKSSL KTIGAFFGGR DHSTVIYACQ TVEDLIDTDK KFKAYVHDIQ KKLKMS
//
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