ID A0A0C1L330_9BACT Unreviewed; 468 AA.
AC A0A0C1L330;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:KIC94397.1};
GN ORFNames=OI18_12335 {ECO:0000313|EMBL:KIC94397.1};
OS Flavihumibacter solisilvae.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Flavihumibacter.
OX NCBI_TaxID=1349421 {ECO:0000313|EMBL:KIC94397.1, ECO:0000313|Proteomes:UP000031408};
RN [1] {ECO:0000313|EMBL:KIC94397.1, ECO:0000313|Proteomes:UP000031408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-3 {ECO:0000313|EMBL:KIC94397.1,
RC ECO:0000313|Proteomes:UP000031408};
RA Zhou G., Li M., Wang G.;
RT "Genome sequence of Flavihumibacter solisilvae 3-3.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIC94397.1}.
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DR EMBL; JSVC01000013; KIC94397.1; -; Genomic_DNA.
DR RefSeq; WP_039140157.1; NZ_JSVC01000013.1.
DR AlphaFoldDB; A0A0C1L330; -.
DR STRING; 1349421.OI18_12335; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000031408; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF12; BLL1977 PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000031408}.
FT DOMAIN 1..133
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 156..381
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 468 AA; 52936 MW; 261632166EA681D6 CRC64;
MKIKMILPAL TEAKSPFWRP IKYSLFPPLG LATLAAYCSP DDVIELQDEH VETLVTDDQP
DLVVIQVYIT NAFRAYALAD QYRSRGVYVC LGGLHVSSLP EEAMPHADSI FIGPGEDTFP
QFLQDYRNGQ PKKRYVNAVR DIQTLPPIRR DLIKRDLYLV PNSIVVSRGC PHHCDFCYKD
AFFEGGRSFY TQKVDAALAE IDRLPGRHLY FLDDHLLGNQ KFSSALFEGM KGMGRLFQGA
STVDAILRGD LIEKAAAAGL RSVFIGFESL SQSNLVQSNK KQNLDKDYGE AIRRLHSLGI
MINGSFVFGL DDDDKDVFKR TVDWAVGSGL TTCTFHILTP YPGTRLFQQM EAEGRILHRN
WDLYDTRQAV YKTVGLTAGE LKAGYDWAYR NFYSWSNVFK ASMQHGQWEM SIKHFAYAGG
WKKFEPLWNM MIKTRGLNKM LPLLESILSR KGKSTNVLQP PSPFPAIA
//
