ID A0A0C1QP76_9CYAN Unreviewed; 288 AA.
AC A0A0C1QP76;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:KIE07324.1};
DE SubName: Full=NAD(P)-dependent oxidoreductase {ECO:0000313|EMBL:KAF3889214.1};
GN ORFNames=DA73_0240160 {ECO:0000313|EMBL:KIE07324.1}, DA73_0400029840
GN {ECO:0000313|EMBL:KAF3889214.1};
OS Tolypothrix bouteillei VB521301.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC Tolypothrix.
OX NCBI_TaxID=1479485 {ECO:0000313|EMBL:KIE07324.1};
RN [1] {ECO:0000313|EMBL:KIE07324.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VB521301 {ECO:0000313|EMBL:KIE07324.1};
RX PubMed=25700407;
RA Chandrababunaidu M.M., Singh D., Sen D., Bhan S., Das S., Gupta A.,
RA Adhikary S.P., Tripathy S.;
RT "Draft Genome Sequence of Tolypothrix boutellei Strain VB521301.";
RL Genome Announc. 3:e00001-15(2015).
RN [2] {ECO:0000313|EMBL:KAF3889214.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VB521301 {ECO:0000313|EMBL:KAF3889214.1};
RA Sarangi A.N., Mukherjee M., Ghosh S., Singh D., Das A., Kant S., Prusty A.,
RA Tripathy S.;
RT "Improved Assembly of Tolypothrix boutellei genome.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIE07324.1}.
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DR EMBL; JHEG04000001; KAF3889214.1; -; Genomic_DNA.
DR EMBL; JHEG02000059; KIE07324.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C1QP76; -.
DR STRING; 1479485.DA73_0240160; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000029738; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000029738}.
FT DOMAIN 3..164
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 167..285
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 173
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 288 AA; 30539 MW; F85D2381FA8CA7BC CRC64;
MKRIAVLGAG AMGSRIVQNL LNAKYQVVVY NRTASKVKPL LDRGAVYATT PKEAAEQADI
VISMVTDNDV SRSIWLDPKI GAALGLSKDA ITIESSTLTV DWTRELADEI LNRGAAFLDA
PVVGSRQQAE AKKLIYLVGG KAQTLAQVQP VLLSAGASSI HHIGSVGQGM TMKLAVNALF
GIQVAALAEI IGMLDKNGIT SVKAMQYLGD LPVISPAALG AGSLMAINNH APMFPIELVE
KDFRYFIQTA QAFGALIPAS TAIHNIYQEA MAFGYGNDNI TGVVQIFI
//
