ID   A0A0C1R4E4_9CYAN        Unreviewed;       926 AA.
AC   A0A0C1R4E4;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Insulinase family protein {ECO:0000313|EMBL:KAF3886617.1};
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:KIE10628.1};
GN   ORFNames=DA73_0219120 {ECO:0000313|EMBL:KIE10628.1}, DA73_0400014880
GN   {ECO:0000313|EMBL:KAF3886617.1};
OS   Tolypothrix bouteillei VB521301.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC   Tolypothrix.
OX   NCBI_TaxID=1479485 {ECO:0000313|EMBL:KIE10628.1};
RN   [1] {ECO:0000313|EMBL:KIE10628.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=VB521301 {ECO:0000313|EMBL:KIE10628.1};
RX   PubMed=25700407;
RA   Chandrababunaidu M.M., Singh D., Sen D., Bhan S., Das S., Gupta A.,
RA   Adhikary S.P., Tripathy S.;
RT   "Draft Genome Sequence of Tolypothrix boutellei Strain VB521301.";
RL   Genome Announc. 3:e00001-15(2015).
RN   [2] {ECO:0000313|EMBL:KAF3886617.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=VB521301 {ECO:0000313|EMBL:KAF3886617.1};
RA   Sarangi A.N., Mukherjee M., Ghosh S., Singh D., Das A., Kant S., Prusty A.,
RA   Tripathy S.;
RT   "Improved Assembly of Tolypothrix boutellei genome.";
RL   Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIE10628.1}.
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DR   EMBL; JHEG04000001; KAF3886617.1; -; Genomic_DNA.
DR   EMBL; JHEG02000048; KIE10628.1; -; Genomic_DNA.
DR   RefSeq; WP_038074846.1; NZ_JHEG04000001.1.
DR   AlphaFoldDB; A0A0C1R4E4; -.
DR   STRING; 1479485.DA73_0219120; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000029738; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   PANTHER; PTHR11851:SF229; PEPTIDASE M16 DOMAIN PROTEIN; 1.
DR   Pfam; PF00675; Peptidase_M16; 2.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029738}.
FT   DOMAIN          60..205
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          212..398
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          529..637
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          677..856
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   REGION          253..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   926 AA;  100668 MW;  AD2CB5941B4761CE CRC64;
     MSFLAKIRPS ILILSILILS GMLWVRDFSV AALQPEVTPV AGLSLTQGVR KTVLENGLTV
     LTKEVHTAPV VSVQVWYRVG SRNEQAGENG ISHQLEHLMF KGTTDRPVQF GRLLSALGSQ
     FNAFTSYDET AYFSTVQQDK LDALLTLEAD RMESALIQAD QLTSEKRVVI SELQGYENSP
     GYRLSRAVMR AAFPKRAYGL PVGGTKADVE QFTLEQVRNY YQTYYSPDNA TLVVTGDFDT
     QAVLKSIQQS FGKLPKRGQG ETGTRGHREL VPSSPRPISP SSRSPIVLKE PGSAALLQAV
     YPLPDANHPD VAAIDVMDAI LTGGRSSRLY QALVESGLAS SVSASPAELL EPGWYEINVT
     AVPGQQLSKI SQVLQQSLTE LQQKQVASDE LNRAKTQLQA SFVLNNQDIT SLATQLGYSQ
     TVSGDYLYIK RYLEAIGKVS AADVQRAAKT YLNPAQQTIG FFEPTVRDAK SGEKSASSGR
     TVENFSPGKP VDPAELAKYL PAAKATRVST KQPLPEQFIF KNGLQVLLLP DRSVPTVNLS
     GQILAGSVFD TDRKAGLANL VAANLMNGTQ TKDALTLAKT LEDRGASLGF QANREGVSIS
     GNGLSANLSI LLDTLADVVQ NANFPNAQLE LSRQRSLTSL KVQLDDPRGL GRRVFQQAIY
     PENHPFHSFP TEQSLKSITR DDLVRFYQEH YRPDTMTVAL VGDFEPSQVK VLLKKAFGEW
     KAEGNPPALN LASVSLPQNT TQLNPVIPGK AEDVTYIGYN SISRKDPRYY TALVLNEILG
     GDTLSSRLGT EVRDRQGLTY GIYSVFAAGI NPGPFLIQMQ TAPGDTRKAI ASTVALLKQL
     RDQGITEAEL NAAKRSITNS YPVELANPSN VADVILGNAI YGLSPAEIRE YPKRIEAVTI
     AQVQQVIQEL IHPDKLVIVT AGPGAQ
//