ID A0A0C1UNT9_9CYAN Unreviewed; 1106 AA.
AC A0A0C1UNT9;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=QQ91_007630 {ECO:0000313|EMBL:NEV66986.1};
OS Lyngbya confervoides BDU141951.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=1574623 {ECO:0000313|EMBL:NEV66986.1, ECO:0000313|Proteomes:UP000031561};
RN [1] {ECO:0000313|EMBL:NEV66986.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BDU141951 {ECO:0000313|EMBL:NEV66986.1};
RA Malar M.C., Sen D., Tripathy S.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:NEV66986.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BDU141951 {ECO:0000313|EMBL:NEV66986.1};
RX PubMed=25745003;
RA Chandrababunaidu M.M., Sen D., Tripathy S.;
RT "Draft Genome Sequence of Filamentous Marine Cyanobacterium Lyngbya
RT confervoides Strain BDU141951.";
RL Genome Announc. 3:e00066-e00015(2015).
RN [3] {ECO:0000313|EMBL:NEV66986.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BDU141951 {ECO:0000313|EMBL:NEV66986.1};
RA Sarangi A.N., Ghosh S., Mukherjee M., Tripathy S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NEV66986.1}.
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DR EMBL; JTHE02000003; NEV66986.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C1UNT9; -.
DR REBASE; 108450; Lco141951ORF18855P.
DR Proteomes; UP000031561; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR046816; MmeI_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR025931; TaqI_C.
DR PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF20473; MmeI_Mtase; 1.
DR Pfam; PF12950; TaqI_C; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:NEV66986.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 467..616
FT /note="MmeI-like DNA-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF20473"
FT DOMAIN 823..967
FT /note="TaqI-like C-terminal specificity"
FT /evidence="ECO:0000259|Pfam:PF12950"
SQ SEQUENCE 1106 AA; 126560 MW; 0B9E4D695753E95F CRC64;
MTGKAAGALF NQKTVENALK GFTFPPDLAD RHQKVQEWIT SLKSGRLAKV KEVSLHGPFL
NDIFQTVLGY RSIIGGDRWE LHAEQTIADG GGSADGAIGL FHAKTEDSGK VKLQGRVVAP
IELKGVTNDL DRAVKGRHES AVDQGWRYAN YTPDCRWVIV SNYREIRLYQ TSKTPAYYER
FRLEDLEDLD TFKQFYFLLC RNNFLPASAD PKAKSRIDQL LIESANADED ITKALYQDYK
KVRLAIAKHF LHMGPADLSE RNITLIAAAQ KVLDRILFIA FCEDRGLLPE KTLQQAHDHQ
DPYSPRTIWE NFKAVFQAVD KGNSALSIPG YNGGLFAHDP LLDEQLMVSD ILCSQLNQLT
TYDFESEVSV NILGHIFEQS VSDLEELRAQ ATHQAYDQKQ GRRKTQGVYY TPAFITQYIV
GVALGEYLER KKDALWEAMG IDQIRANAVR QRQRAEIQFW ERYRDEVLTQ TRVIDPACGS
GAFLIAAFDF LNRKYEEVNE RLAALKTEDE SGEFVGQRSL FDLTKTILNQ NLYGVDLSPE
SVEITKLSLW LKTAERGKTL TYLDNNIKVG NSIIADPAFD PAYAFDWEAA FPVVFASGGF
DVVIGNPPYV RQELLTPFKP YLQEHYAAYD GVADIYVYFY EKGLNILRPN GILSYIVTNK
WLRAGYGEPL RQFFSENSVF EQIIDFGHAP IFEDADVFPC IVSVRKPEAV EAKEIEKPEA
AAPVQVCPVP REHLENINLP QYINQEGYEV PWARYGKEEW SLESPAVEQL MDKLKVVGVC
LNDFLGTPPL YGLKTGYNKA FLIDQETRDE IVSKDSQSVQ IIKPYLRGQD INRWNSEWQK
LWMIMTTPDI RIEQYPGVKE HLEQHRERLD SRAGRQEWWQ LQSMPAQYKR FEKPKIIYQE
IQFHPSYCYD TEGYYTNNKC FILATEELFP LAVLNSPIGW WHNWRYLPHM KDEALTPKGE
LIENFPIAPP TDEIRAEVEP AVQQLIEFTK ANQEATRDIL DWLQLEHGIE KPGNKLSDFA
SLPLDDFLKE VKKRRPKAAG SLGPKPLKEL KAAYSDYAHP IQQRRNAGLT LEHRISDLVN
QAYGLTPEEI DLMWKTAPPR MPFNRP
//
