GenomeNet

Database: UniProt
Entry: A0A0C1XL72_9ACTN
LinkDB: A0A0C1XL72_9ACTN
Original site: A0A0C1XL72_9ACTN 
ID   A0A0C1XL72_9ACTN        Unreviewed;       573 AA.
AC   A0A0C1XL72;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-SEP-2017, entry version 24.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KIF75518.1};
GN   ORFNames=QR77_19665 {ECO:0000313|EMBL:KIF75518.1};
OS   Streptomyces sp. 150FB.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1576605 {ECO:0000313|EMBL:KIF75518.1, ECO:0000313|Proteomes:UP000031584};
RN   [1] {ECO:0000313|EMBL:KIF75518.1, ECO:0000313|Proteomes:UP000031584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=150FB {ECO:0000313|EMBL:KIF75518.1,
RC   ECO:0000313|Proteomes:UP000031584};
RA   Tarkka M.T., Feldhahn L., Kruger D., Buscot F., Wubet T.;
RT   "Genome sequence of the mycoparasite antagonist Streptomyces sp.
RT   strain FB 150.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIF75518.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; JTHL01000001; KIF75518.1; -; Genomic_DNA.
DR   EnsemblBacteria; KIF75518; KIF75518; QR77_19665.
DR   Proteomes; UP000031584; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031584};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031584}.
FT   DOMAIN      266    394       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      480    549       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     274    281       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   573 AA;  64355 MW;  4D42A0A2FFA7ED5B CRC64;
     MLEQLLREGQ QGVEPKDKQW LERCQPLVLV ADTALLAVPN EWGKRVLEGR LAPLIVETLS
     HECGRPIRIA ITVDDSVAGP TPPAPPIPQQ HRYQGPPHDD QRQNDAYDDY GHRPPDDGMP
     SVRPAYPDYQ QQRPDPGAWP RTEEDLSWQQ QRLSGYQDRD PYTGPRTQQP QHDYRQPQGP
     ERPQYEQHER HDLQDPQSPR HNGGHNGGRH RGAPGPLGAQ PAPAPGPGEP HARLNPKYLF
     DTFVIGASNR FAHAAAVAVA EAPAKAYNPL FIYGESGLGK THLLHAIGHY ARSLYPGTRV
     RYVSSEEFTN EFINSIRDGK GDTFRKRYRD VDILLVDDIQ FLASKESTQE EFFHTFNTLH
     NANKQIVLSS DRPPKQLITL EDRLRNRFEW GLTTDVQPPE LETRIAILRK KAVQEQLNAP
     PEVLEFIASR ISRNIRELEG ALIRVTAFAS LNRQPVDLGL TEIVLKDLIP GGEDAAPEIT
     AAAIMAATAD YFGLTVDDLC GSSRSRVLVT ARQIAMYLCR ELTDLSLPKI GAQFGGRDHT
     TVMHADRKIR ALMAERRSIY NQVTELTNRI KNG
//
DBGET integrated database retrieval system