ID A0A0C2FES3_9ACTN Unreviewed; 786 AA.
AC A0A0C2FES3;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Arylsulfatase {ECO:0000313|EMBL:KIH97679.1};
GN ORFNames=LP52_17790 {ECO:0000313|EMBL:KIH97679.1};
OS Streptomonospora alba.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Streptomonospora.
OX NCBI_TaxID=183763 {ECO:0000313|EMBL:KIH97679.1, ECO:0000313|Proteomes:UP000031675};
RN [1] {ECO:0000313|Proteomes:UP000031675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90003 {ECO:0000313|Proteomes:UP000031675};
RX PubMed=25601074; DOI=10.1016/j.chembiol.2014.11.017;
RA Metelev M., Tietz J.I., Melby J.O., Blair P.M., Zhu L., Livnat I.,
RA Severinov K., Mitchell D.A.;
RT "Structure, bioactivity, and resistance mechanism of streptomonomicin, an
RT unusual lasso Peptide from an understudied halophilic actinomycete.";
RL Chem. Biol. 22:241-250(2015).
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIH97679.1}.
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DR EMBL; JROO01000033; KIH97679.1; -; Genomic_DNA.
DR RefSeq; WP_040275138.1; NZ_JROO01000033.1.
DR AlphaFoldDB; A0A0C2FES3; -.
DR STRING; 183763.LP52_17790; -.
DR Proteomes; UP000031675; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16025; PAS_like; 1.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR PANTHER; PTHR42693:SF43; BLL2667 PROTEIN; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000031675}.
FT DOMAIN 46..460
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 87329 MW; DDDE3AB4E0BF1146 CRC64;
MSDAGPNRYN LPIEERGHAP ATSMDVREQD PPYQPADPLR PPQGAPNVVL VLLDDMGFGA
PSAFGGPCEM PTADRLARDG LRYTRFHVTA VCSPTRQSLL TGRNHHSVGM GVTTEMSSAA
PGYSGIRPRS AATVAETLRA NGYNTGAFGK WHQTPARDVS PAGPFDRWPT GEGFEKFYGF
LCAEMNHWYP ALFDGTVPTE PSKTPREGYH LSEDLIDQAI EWVGTQQSLK PDIPFFAYLP
FGATHAPYHV PKEYREKYRG KFDHGWDRQR EITLERQKEL GVVPQDAELA PWAEGVPHWD
ELSDAEKRSA ASLMELYAGF AEHTDAQIGR LVDALEENGQ LDDTLFIYIL GDNGASAEGG
LGGTLNEHRY ASGIPDSAEF INAHDEALGD ETTHAHYPVG WALAMNTPYQ WTKQVASHFG
GTRDGMITHW PNGIRERGGL RHQFHHVIDV LPTILEAAGV PEPDSVDGIA QQPVEGTSML
YSFNESDAAD RRRLQYFEMV GNRGIYHDGW MAVTRHGTPW EMVQNGRRYF DDDVWELYDT
NVDWTQARDI SAEHPGKLHQ LKQLFLTEAA KYNVFPLDDR MTERENPREA GRLDLFGDRK
SVTFNGPGLR LTEETAPNVK NRSHTVTACV EVPEEGAEGV LVAQGGRFGG WSLYVHEGRP
RYAYNYFGLQ VHTAAGEDPL SPGEHEIRVD FSYDGGGVGR GGDVSLLVDG KQVAEGRVDA
TIPYYFAFDE TFDLGVDRLS PVTDDYPTAD NAFTGRLRRV RVDLGDDLCS DSDSEVQREQ
FRAAHE
//
