ID A0A0C2JBM7_9ACTN Unreviewed; 250 AA.
AC A0A0C2JBM7;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=ABC-2 type transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF12698};
GN ORFNames=LP52_11175 {ECO:0000313|EMBL:KIH98816.1};
OS Streptomonospora alba.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Streptomonospora.
OX NCBI_TaxID=183763 {ECO:0000313|EMBL:KIH98816.1, ECO:0000313|Proteomes:UP000031675};
RN [1] {ECO:0000313|Proteomes:UP000031675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90003 {ECO:0000313|Proteomes:UP000031675};
RX PubMed=25601074; DOI=10.1016/j.chembiol.2014.11.017;
RA Metelev M., Tietz J.I., Melby J.O., Blair P.M., Zhu L., Livnat I.,
RA Severinov K., Mitchell D.A.;
RT "Structure, bioactivity, and resistance mechanism of streptomonomicin, an
RT unusual lasso Peptide from an understudied halophilic actinomycete.";
RL Chem. Biol. 22:241-250(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIH98816.1}.
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DR EMBL; JROO01000019; KIH98816.1; -; Genomic_DNA.
DR RefSeq; WP_040273066.1; NZ_JROO01000019.1.
DR AlphaFoldDB; A0A0C2JBM7; -.
DR STRING; 183763.LP52_11175; -.
DR OrthoDB; 9786643at2; -.
DR Proteomes; UP000031675; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR000412; ABC_2_transport.
DR PANTHER; PTHR43229:SF3; ABC-TYPE MULTIDRUG TRANSPORT SYSTEM, PERMEASE COMPONENT; 1.
DR PANTHER; PTHR43229; NODULATION PROTEIN J; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR PIRSF; PIRSF006648; DrrB; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031675};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..235
FT /note="ABC-2 type transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF12698"
SQ SEQUENCE 250 AA; 27125 MW; 8BC5B124F77E3BBB CRC64;
MKGGYLKLEL RRVLREPGTI LFVLGFPAAF YVLEVIIFQG QWPEEKAQYE PAAVLMPAMA
AWGVLISGML VGTRVVNERK AGWQRQLRLT PLTSGHYLLG KAAVGMAVAV PPPFVVALVG
ALFLDVRLEP TGWLFVTLLV SIGGLPFAVL GLFIGQMGTR ENVQQITIIG MLVLAIFGGI
FIPLQSLPTW FTYISYVTPS YWLSELGKSG LSGEGVGAQN PVLAGAVLLA WSVVLAAAVI
WRYRHDSART
//
