ID A0A0C2LSH1_9CYAN Unreviewed; 230 AA.
AC A0A0C2LSH1;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=2-phytyl-1,4-naphtoquinone methyltransferase {ECO:0000256|HAMAP-Rule:MF_01982};
DE EC=2.1.1.329 {ECO:0000256|HAMAP-Rule:MF_01982};
DE AltName: Full=Demethylphylloquinone methyltransferase {ECO:0000256|HAMAP-Rule:MF_01982};
GN Name=menG {ECO:0000256|HAMAP-Rule:MF_01982};
GN ORFNames=SD81_13910 {ECO:0000313|EMBL:KIJ77726.1};
OS Tolypothrix campylonemoides VB511288.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC Tolypothrix.
OX NCBI_TaxID=1245935 {ECO:0000313|EMBL:KIJ77726.1};
RN [1] {ECO:0000313|EMBL:KIJ77726.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VB511288 {ECO:0000313|EMBL:KIJ77726.1};
RA Tripathy S., Das S., Gupta A., Malar M.C., Adhikary S.P.;
RT "Draft whole genome shotgun sequence of Tolypothrix campylonemoides
RT VB511288.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Methyltransferase required for the conversion of 2-
CC phytyl-1,4-beta-naphthoquinol to phylloquinol. {ECO:0000256|HAMAP-
CC Rule:MF_01982}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=demethylphylloquinol + S-adenosyl-L-methionine = H(+) +
CC phylloquinol + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:40551,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28433, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:87844; EC=2.1.1.329;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01982};
CC -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01982}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. MenG/UbiE family. {ECO:0000256|HAMAP-Rule:MF_01982}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIJ77726.1}.
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DR EMBL; JXCB01000007; KIJ77726.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2LSH1; -.
DR OrthoDB; 9808140at2; -.
DR UniPathway; UPA00995; -.
DR GO; GO:0052624; F:2-phytyl-1,4-naphthoquinone methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01982; MenG_phylloquinone_subfam; 1.
DR HAMAP; MF_01813; MenG_UbiE_methyltr; 1.
DR InterPro; IPR032904; MenG.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR NCBIfam; TIGR01934; MenG_MenH_UbiE; 1.
DR PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43591:SF106; METHYLTRANSFERASE-LIKE PROTEIN 27; 1.
DR Pfam; PF01209; Ubie_methyltran; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51608; SAM_MT_UBIE; 1.
DR PROSITE; PS01183; UBIE_1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|HAMAP-
KW Rule:MF_01982};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691, ECO:0000256|HAMAP-
KW Rule:MF_01982};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_01982}; Ubiquinone {ECO:0000313|EMBL:KIJ77726.1}.
SQ SEQUENCE 230 AA; 26028 MW; B06CA4597BA46865 CRC64;
MTDNIRTIFN RIAPVYDQLN DWLSLGQHHV WKEMTVKWSA AKPEDTSLDL CCGSGDLSFR
LARRVGRNGQ VYAVDFSSQL LEIAKKRCQT YYLQPNITWV EADVLSLPFE DNQFDAATMG
YGLRNVTDIT RSLKELHRVL KAGAKAAILD FHRPSNPQLR AFQQWYLSNL VVPIANNLGL
KEEYAYISPS LDRFPTGNEQ VEIARQVGFA AATHYPIANG MMGVLVITKF
//
