ID A0A0C2M1D8_THEKT Unreviewed; 302 AA.
AC A0A0C2M1D8;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=FYVE, RhoGEF and PH domain-containing protein 4 {ECO:0000313|EMBL:KII60890.1};
GN ORFNames=RF11_06113 {ECO:0000313|EMBL:KII60890.1};
OS Thelohanellus kitauei (Myxosporean).
OC Eukaryota; Metazoa; Cnidaria; Myxozoa; Myxosporea; Bivalvulida;
OC Platysporina; Myxobolidae; Thelohanellus.
OX NCBI_TaxID=669202 {ECO:0000313|EMBL:KII60890.1, ECO:0000313|Proteomes:UP000031668};
RN [1] {ECO:0000313|EMBL:KII60890.1, ECO:0000313|Proteomes:UP000031668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wuqing {ECO:0000313|EMBL:KII60890.1};
RX PubMed=25381665; DOI=10.1093/gbe/evu247;
RA Yang Y., Xiong J., Zhou Z., Huo F., Miao W., Ran C., Liu Y., Zhang J.,
RA Feng J., Wang M., Wang M., Wang L., Yao B.;
RT "The genome of the myxosporean Thelohanellus kitauei shows adaptations to
RT nutrient acquisition within its fish host.";
RL Genome Biol. Evol. 6:3182-3198(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KII60890.1}.
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DR EMBL; JWZT01005397; KII60890.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C2M1D8; -.
DR EnsemblMetazoa; KII60890; KII60890; RF11_06113.
DR Proteomes; UP000031668; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR PANTHER; PTHR12673:SF254; RHOGEF DOMAIN-CONTAINING PROTEIN GXCH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000031668}.
FT DOMAIN 1..170
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
SQ SEQUENCE 302 AA; 34515 MW; E3C13F16DD7FBD2B CRC64;
MLDELFRKPF LLKADPSEKS YPSAKTIEDM FSNLVCIIGF HTNFFLPMIK ERVESWTEDS
EIGDIFTKLA PLFNLYTIYC QSYDNCSGII TNIAKKFPKF AADLNNIEKK KECKNLRLTH
HMLDLIQRIP RYNLMLNEIL KHSEPQSAKY ENIKNALNLM SAAAHKANDR LTESFNDYII
CCVKQSSSKY RKKAEFEFST VGLLKDPDDK IPTAFGISNL NELMILKSAT LEDKNSWIDE
ISNVISTHDA SSTESNTVSL HTVMVSLVSV RPNEKAEWIQ KQLTLTSENK IMIVDQSKVL
PV
//
