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Database: UniProt
Entry: A0A0C2QQ86_9CYAN
LinkDB: A0A0C2QQ86_9CYAN
Original site: A0A0C2QQ86_9CYAN 
ID   A0A0C2QQ86_9CYAN        Unreviewed;       460 AA.
AC   A0A0C2QQ86;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   27-SEP-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SD80_28325 {ECO:0000313|EMBL:KIJ80480.1};
OS   Scytonema tolypothrichoides VB-61278.
OC   Bacteria; Cyanobacteria; Nostocales; Scytonemataceae; Scytonema.
OX   NCBI_TaxID=1233231 {ECO:0000313|EMBL:KIJ80480.1, ECO:0000313|Proteomes:UP000031959};
RN   [1] {ECO:0000313|EMBL:KIJ80480.1, ECO:0000313|Proteomes:UP000031959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VB-61278 {ECO:0000313|EMBL:KIJ80480.1,
RC   ECO:0000313|Proteomes:UP000031959};
RA   Tripathy S., Das A., Panda A., Malar M.C., Adhikary S.P.;
RT   "Draft genome sequence of Scytonema tolypothrichoides VB-61278.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIJ80480.1}.
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DR   EMBL; JXCA01000015; KIJ80480.1; -; Genomic_DNA.
DR   RefSeq; WP_048871592.1; NZ_JXCA01000015.1.
DR   EnsemblBacteria; KIJ80480; KIJ80480; SD80_28325.
DR   Proteomes; UP000031959; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000031959};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031959}.
FT   DOMAIN      151    279       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      360    429       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     159    166       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   460 AA;  52862 MW;  7B02ED7923EC939C CRC64;
     MEMPIENLWS QVLERLQLEL SRPTFETWIK TASAERLENN CLVIFTPNPF ARNWLQKYYI
     KTIANVVQDI LGYPVDIYIT VTQGDEVSQV NEQEVSWGFR TQTSPSETLP QNRLKTTELN
     LKYVFSRFVV GANNRMAHAA ALAVAEYPGR EFNPLFLCGG VGLGKTHLMQ AIGHYRWEIS
     PDSRIFYVSC EQFTNDLIAA IRKDSMQSFR EHYRAADVLL VDDIQFIEGK EYTQEEFFHT
     FNTLHEAGKQ VVLASDRPPN QIPGLQQRLC SRFSMGLIAD IQPPDLETRM AILQKKAEYE
     NIRLPRDVVE YIAFHYTSNI RELEGALIRA LAYISIWGLP MTVENIAPVL EPPTQKLEAT
     PEAILSLVAE VFDISIEDLK GNSRRREISW ARQIGMYLMR QHTVLSFPRI GEEFGGKDHT
     TVIYSCEKIT QLRQTDQNLV KTLRQLSDRI NMASRPHKLS
//
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