ID A0A0C3CLZ6_HEBCY Unreviewed; 1931 AA.
AC A0A0C3CLZ6;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Actin cytoskeleton-regulatory complex protein pan1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=M413DRAFT_15631 {ECO:0000313|EMBL:KIM49715.1};
OS Hebeloma cylindrosporum h7.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Hebeloma.
OX NCBI_TaxID=686832 {ECO:0000313|EMBL:KIM49715.1, ECO:0000313|Proteomes:UP000053424};
RN [1] {ECO:0000313|EMBL:KIM49715.1, ECO:0000313|Proteomes:UP000053424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=h7 {ECO:0000313|Proteomes:UP000053424};
RG DOE Joint Genome Institute;
RA Kuo A., Gay G., Dore J., Kohler A., Nagy L.G., Floudas D., Copeland A.,
RA Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A.,
RA Lipzen A., Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=h7 {ECO:0000313|Proteomes:UP000053424};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KN831768; KIM49715.1; -; Genomic_DNA.
DR STRING; 686832.A0A0C3CLZ6; -.
DR HOGENOM; CLU_235129_0_0_1; -.
DR OrthoDB; 2734911at2759; -.
DR Proteomes; UP000053424; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00052; EH; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR000261; EH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR46006:SF5; DH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1.
DR Pfam; PF12763; EF-hand_4; 1.
DR Pfam; PF16652; PH_13; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00027; EH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50031; EH; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000053424};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 56..145
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT DOMAIN 952..969
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1195..1254
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1619..1785
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1822..1915
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1270..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1469..1524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1539..1561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1574..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..479
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..617
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..742
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..824
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..860
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 916..946
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1298..1332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1355..1371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1469..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1507..1522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1539..1555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1931 AA; 210987 MW; A0F68E8453902CA0 CRC64;
MSQTFMPINT SAPYGAGGVP QLPQQQQNLV QSIQQHNQAQ RGSSGQQLSW DLTKAEKKNY
DNIFRSWDAK GTGFINGGTA LEVFGASGLP KDDLARIWTL ADRDDRAKLN IAEFHVAMAL
IYRRLNGMPV PDELPAQLVP PSSRDLDQSV GFLKDILKHD TTNRSRSPSS LDTPISRLKD
RSFDRSSPSA LQGRDATIYK HDDSEPRGFF KPSNRHIDRS AIRSRADEDS PSADLSDMKR
QLENTAQRLD RAAEADAAKT KEDEELDQEM DDLKYRVKRV QDDLDYVARG PKTSSRDEER
RRLERELLSL MHERIPEVER KIKARDERKE KERRQWARDR DRANERFRRY DSKDEYSSRR
DDDRDRPYSR GGDDRDRPYS RGGDDRDRPY SRGDNRDRPY SRAGDRDRPY SRGAYDRDDR
DRDGYRRERT SSRSSRDYDR PRSPATNDQR SAPPPPAPPA ITIRDAPPPP SPSKPTPSPI
SKTMSPAERQ AFARAEAQRR IQERMAKLGV TAPASSPTID SSVEDRLQQE KKEAEEKAKA
AERQAEERER ARKERLASEK ALKEEKSPVT PTTPTPTPTP TPTPTVTAAP PAPTPRVAPP
APKPRAPAPP PPRKAAASAA PRTPVAVAAP PPVVKPPVVV REIPKEPEVD PQEEALRARE
AALAKQKEER EARFQERLRQ LEKEEEEARM EEERYQARLQ AVKARSAAKV ATPPPAPAPP
APPAPAPAAP PAPAPVAAKT TPPPAVVVVP VPAATPAFAE PVSAPPVEKS TNPFSRLIKS
GGSTPAPPAT INTTMNTNGS TNPWARPQTA PPPTSAPPPS KSPAPTSAKT AYQTAPSEIE
EDDWDVVREK EEDDDDSSDD EITQSRSVRA NIAQQLFGGM LPRPTSGGAV SKPSSPAPGG
GGGFGGGGGG GFGASSTPPP PAPGAPPPPP PAPAAPRAPF AVPAPASAGP PDTNALMSSI
QGGLKLRPTK TVDKSAPPVS GRVIGDVAPP AHINVVPVVV AREASPPPPP ARMDQAANPY
AADPYAYGAE THSESMMPGP PLMNTDEMGS KSMNRQSVGW FADRAADVGG LSPVDVERLP
STVEEQEDGE DMYEKASAPP PVAEVVAPTL GVPEILVDGP ASEPQSGLMA DIDKGVEYRV
RSLYAFEGDG PEDLSFGENL IIIANPSKTD GDWWYGKTLS TGKSGLFPKT YVETVITKKA
KAVYSYTGDN PDELAFNEGD VLSIVDTSEE EWWKAEQGGV VFIVPAAYLE LVEATPAAVV
TIADDDESVL EFDSDDSSSS ESSDYLSFED SESGDIVDGA DDDGKTSTHH HHNNSTNKAD
KEARERERQR VLEAAGLIVQ RDVGPPPARP SRPPRSRGAS STSNSSSVAS RKRRPAPAAP
QRVVSGVHKE LPPVPPVLSV EMDGMVVGLE DVEPEEQDEE EQEEQGEEAL THEARLDDAF
ARYESFKNAQ ASNQLVNNRL SVVSTDSSIT MPASPATTVS SMSMSQTQAQ TQNQNQSQNQ
PQHHPPSMLH MHKDKDHPSG TSEGRYAHFL NFLTSTGNRV TSSSFSSSSS AAGESGGERR
RSVGLLNISA PIMSKSNNSS FQTTPQDGPS RASSPAFGMS WASLVDKDAL DGIPPGERKR
QEAIFELINT EVFYQSMLPM LSGKEITVVF ANIEDLLLTN TAFVSSLEER QKECRLYVDR
IGDILLSHIP NMGVYMEYCV NQSIAIQVLK SLRDSNPELA SHLKQLRDEN PTVRNLDLSS
YLLAPMQRIT KYPLLMKQAK VGEEHEGILT SREMAEKLLE HINETIREQE SHETLKNISQ
NLWIGTGRLD LTAPTRHMGP RRLLKQGHLM KAKSGKKLHA FLCSDTLVLL DDAMKNLYRM
PIPLAHSQVK ESGARDDTVF LISQAYPRGG DSIALRAPSA RDCQQWVQEI ANASKRARNA
EDRANRRSSR R
//
