ID A0A0C3CYB2_HEBCY Unreviewed; 1209 AA.
AC A0A0C3CYB2;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=M413DRAFT_437999 {ECO:0000313|EMBL:KIM48826.1};
OS Hebeloma cylindrosporum h7.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Hebeloma.
OX NCBI_TaxID=686832 {ECO:0000313|EMBL:KIM48826.1, ECO:0000313|Proteomes:UP000053424};
RN [1] {ECO:0000313|EMBL:KIM48826.1, ECO:0000313|Proteomes:UP000053424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=h7 {ECO:0000313|Proteomes:UP000053424};
RG DOE Joint Genome Institute;
RA Kuo A., Gay G., Dore J., Kohler A., Nagy L.G., Floudas D., Copeland A.,
RA Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A.,
RA Lipzen A., Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=h7 {ECO:0000313|Proteomes:UP000053424};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN831768; KIM48826.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C3CYB2; -.
DR STRING; 686832.A0A0C3CYB2; -.
DR HOGENOM; CLU_001366_2_1_1; -.
DR OrthoDB; 5477883at2759; -.
DR Proteomes; UP000053424; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000053424};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ SEQUENCE 1209 AA; 136830 MW; 9F24C1622E6068BC CRC64;
MDLCIRYIPH EVNTWTVTRA IASVLHSEDF APIVEGRLIN FRVKLNPNPA GGIRNDGTGL
LTLPTEAVGI KFLAYIFKDP IRINKKKLSF KKADRPPPEG LALTLKKTPY VNPDIEEASD
EKVSLLDTQL RVTAVQFGIF FQRDYEETPL RPRTFSVEWE SKYDSDSRGR GQLSFDYDRK
LIRITLENEL TEDEGYTLII NFASIQKIGT GYDGPAYICF DTLVPPMIER FQIHRPMTGR
RDVDFRKFKQ RVGFLSPTHA PVAPYARHLR VVLFNNPYDD VVGKFRSMCL IAGLSNTMVF
ICRPPLVIEA LRLGFFSPKR IYDLHKTLSG FDWPVAFQLE SLLHNGLLNT DDMDLLIPRV
RELSRKHARQ GAEYAGDLLR RYNEALQLRP AAESPLKCYH HILATFEFTP PASKTFRCHH
VTFTPTRMLL EGPYSSQSNR VIRQYRGYEE HFLRVDFRDE DRLQYRWDRE VDGASFLTER
VGKTLKNGFE LAGRQFEFLA YSSSALRDHA VWFMNPFDHP KMGWVNAESI RSSLGNFEGT
KLSRQPSKFA ARLAQAFTAT DPSVDIRKNE WDIMPDLGKD PYLFTDGVGT ISKALGDRIW
AVLCKDKRNP GYTIQPSAYQ IRFLGFKGVV AVDEQLDKRA DGIQMRLRPS MKKFDVDAEI
APLEIAQAFE APNTCYLNRP LVMVLEDIGV RKEAFQELQD NAVADAKTID DSISKFYDVL
ASHHLGSSYR LREILGRLRD DFNMDLTSNG KTIAMDTPFL RQVRQVAMTD ILRDIKHSAR
IPVPNSYLLV GVADEGPAYV AEGHANVFCL SVGEVYVCVQ SPNETKPTWL TGNASISRSP
VVHPGDVQRV RAIGKPPDDK LCLFRNLVNV VVLPSIGDRS LASCLGGGDV DGDLFAIIFH
DTLMPIYLEP PANYEPLGTL ELDRESTVED ICDFIVEYIN SDVLGLLSDR FLVIADQSSE
GIFDSNCLFL AELCSQAVDY PKQGIAPDLE GDRLPRTLIR CKPDWHAAEV VSPRQTDYYE
SSRALGHLFR SITLEDPTPI PAEDLPPSYA LYDPISVALL EKVQPYLQES AFINHTVEVV
KKLFQTYCDE LRYICATHTI SNTPGVRLLE AEIVVGTILA KCSQKRWRKE RIYRMRLHTG
TLVLDVQHGL LENPKTDSIS ELVHGLGLAW NAWDLSLRKR NDFGANSFGL IALNTIFDCL
KALNKLSIS
//
