ID A0A0C4YDQ7_9BURK Unreviewed; 1881 AA.
AC A0A0C4YDQ7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=RR42_s2220 {ECO:0000313|EMBL:AJG23802.1};
OS Cupriavidus basilensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=68895 {ECO:0000313|EMBL:AJG23802.1, ECO:0000313|Proteomes:UP000031843};
RN [1] {ECO:0000313|EMBL:AJG23802.1, ECO:0000313|Proteomes:UP000031843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4G11 {ECO:0000313|EMBL:AJG23802.1};
RX PubMed=25977418;
RA Ray J., Waters R.J., Skerker J.M., Kuehl J.V., Price M.N., Huang J.,
RA Chakraborty R., Arkin A.P., Deutschbauer A.;
RT "Complete Genome Sequence of Cupriavidus basilensis 4G11, Isolated from the
RT Oak Ridge Field Research Center Site.";
RL Genome Announc. 3:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP010537; AJG23802.1; -; Genomic_DNA.
DR STRING; 68895.RR42_s2220; -.
DR KEGG; cbw:RR42_s2220; -.
DR Proteomes; UP000031843; Chromosome secondary.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AJG23802.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000031843};
KW Transferase {ECO:0000313|EMBL:AJG23802.1}.
FT DOMAIN 39..324
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1521..1593
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1596..1645
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1665..1881
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1881 AA; 206944 MW; 04624162DC160632 CRC64;
MKPVIDWHPR GKISPFGPLD RITGTAIHLP HQAPRNIKYS YRLESGTRQM NPLFYFGHES
GVSFPVVWED DDRVVGRGWL PGRDGMPKAV LAVWHAAEHP RPTSLAHEYG LKDELDGSWA
VRPLELVRER GRTVLLLDDP GGEPLAKLLG TPMEVGRFLR LAISIAAALD QFHQRGLIHK
DIKPAHILVN DAPIEARLTG FGIASRQSRE RQAPAPPEEI AGTLAYMAPE QTGRMNRSID
ARSDLYSLGV TLYQMLTGVL PFATDDPMEL LHSHLARQPV PPAERVPSIP ALLSAMVMKL
LSKTAEERYQ TAAGLEADLR RSSVAWESRG SIATFPLGEH DLPDRPLIPE RLYGREREIE
TLLAAFDRVV TQGTPELVLV SGYAGIGKTS AVLALRSALA LRNGLFASGK FDQYKRDVPY
ATLAQAFQNL VRPLLGKSEA DLAPWRTALA EALGPNGGLM VPLIPELGLI LGPQSPVPEL
PPCDEQHRFQ MVFQRLLAVF AQPTHPLALF LDDLQWLDAA TLDLLEYLAT QPEVRHVLLI
GAYRNDDVKP GHPLLLRLPA IRQAGGRVND ITLSPLGFDD VIRLIVDALH CAPGDAAPLA
RLVQEKTGGN PFFAIQFLTA LTEEGLLVFD HRGARWSWDL EQIRAKGFTD NVVDLMLAKL
RRLPAATRNA LKQLACLGND AAIASLAMVQ DASEAELDAA LRPAVRAGLV LRLGNTYRFL
HDRIQEAAYA LIPEGARPAA HLAIGRRLAT GTPPEAIAER VFEIVGQLNR GTDLITAAEE
REQVAELNLL AGQRAKASTA YASALTYLTA GAALMQGDAW KRRPKFAFAL EFHLAECEFL
TGAPAAADAR LAELACRAAS LPDLASVTQL RLELFLALGQ RERAVEVGLD YLYRAGVQCS
AHPTDEEVLQ EYDRMWRQLG DRPIEALLDL PMMTNAVACE TMDVLTALML PAWYTDVNLG
SLIIGRMANL SLEQGNSDAS CLAYTWLGMI LGPRSGDYKA AFRFGQLGLS LVEQRGLDRF
RARVYQAFGG HVMQWTQPIR AARSLVRRAF DVASKLGDLT YASFARNNLI TQLLACGDPL
AEVQNEAEAT IGFARRASFG LAVDRVTPQL QLARTLRGLT PVFGVFDDDD FNEEEFERYL
DEAPGPALAT CWYWIRKLQA RFLADDHAAA IAAADRAESL LWTSPSFFEQ AEYHFYTALA
RAACCGTAAA PERTQHLAAL AAHHRQLLVW SEHCPENFEN RAALVGAEIA RLDGREVDAM
GLYEQAIRSA QDNDFIHNQA LANELAARFY AARGFEKVAR VYLQDARHGY LRWGAGGKVR
QLDALYPHLW GEERAPAPTT TIGAPVEHLD LATVIAVSQA VSGEIVLDKL LDTLMRTAIE
QAGAERGLLI LPRGSEQRIA AEATTGGDIV TVQLRDESVT ATALPVSMLH YVLRTRENII
LDNAATQMPF SDDPYILQHH ARSILCLPLL TQAKLVGVLY LENNLAPRVF VPTRTTVLKM
LASQAATALE ITCLYRDLAQ REAKIQRLVE ANIIGICLWH MDGRILEAND AFLRMLGYDR
EDLASVPLRW TDLTPPDRRE RDARLVQDLR ISGTLPPFEK EFFRKDGSRV LVLLGCATFE
EGGEQGVSYM LDLTERKRAE EALHQAQAEL AHVTRVTTLN ALTASIAHEV NQPLAAIVTN
ANAALRWLAR QPPDLAEVRD TLGCIVQDGH RAGAVIEGMR ALLKKTAAVT ARLDMNALIE
DAIALIQGEI SRHQVLLRTE LEPDLPPVAG DRVQLQQVLL NLMMNSIEAM KEVAERPRGL
LIRSHLDASG TVLVAVQDAG VGLEPQDLER VFQTFFTTKA EGLGMGLAIC RLIVEAHGGR
LWAYPNVPCG AVFQFTLPPQ D
//
