ID A0A0C4YH43_9BURK Unreviewed; 422 AA.
AC A0A0C4YH43;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Magnesium and cobalt transport protein CorA {ECO:0000313|EMBL:AJG21239.1};
GN ORFNames=RR42_m3880 {ECO:0000313|EMBL:AJG21239.1};
OS Cupriavidus basilensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=68895 {ECO:0000313|EMBL:AJG21239.1, ECO:0000313|Proteomes:UP000031843};
RN [1] {ECO:0000313|EMBL:AJG21239.1, ECO:0000313|Proteomes:UP000031843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4G11 {ECO:0000313|EMBL:AJG21239.1};
RX PubMed=25977418;
RA Ray J., Waters R.J., Skerker J.M., Kuehl J.V., Price M.N., Huang J.,
RA Chakraborty R., Arkin A.P., Deutschbauer A.;
RT "Complete Genome Sequence of Cupriavidus basilensis 4G11, Isolated from the
RT Oak Ridge Field Research Center Site.";
RL Genome Announc. 3:0-0(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; CP010536; AJG21239.1; -; Genomic_DNA.
DR RefSeq; WP_043350329.1; NZ_CP010536.1.
DR AlphaFoldDB; A0A0C4YH43; -.
DR STRING; 68895.RR42_m3880; -.
DR KEGG; cbw:RR42_m3880; -.
DR OrthoDB; 9803416at2; -.
DR Proteomes; UP000031843; Chromosome main.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12822; TmCorA-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031843};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 362..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 105..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 46668 MW; E86035B3904663C6 CRC64;
MQLLGFSASQ VHPLASLDAA RDFLAGNAAA RFVWVDTPIE EISAAPTAWR DSVQALTGAP
VLDLHLIDAT NPSHPSYFDT THVYDMVIFR KLTFETSRLI AEAGAEGTAA SGTSTTATAG
PQPAAKPGTP TKPRRYPPGF LPALAKIDTQ PVTFFVFDNV LLTVRPAQSR TLDQVRQRLL
ELCQAPRPQA ASRTRANGHA ALVHGIRPPT RPEDLMLRLL NAMVDRYLDL RAPLTRQLDR
WQRALLNARR SFSSWEGLLD ARIELRRLEH LCEEQHDALQ EFRDSLLDNS YSIASEGPAA
GTPGTPGAAG RDDALLVRIN DVMEHISRVL AHARRLEDSI ESAVQIHFSS VAHRTNRTMR
TLTLITALFM PLTLITGIFG MNFDRMPWLR EPQGFWWSLG LMGAVVVVLA AVWALGRRLE
QS
//
