ID   A0A0C5GI97_9ACTN        Unreviewed;       462 AA.
AC   A0A0C5GI97;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Protease {ECO:0000313|EMBL:AJP04201.1};
GN   ORFNames=TU94_24770 {ECO:0000313|EMBL:AJP04201.1};
OS   Streptomyces cyaneogriseus subsp. noncyanogenus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=477245 {ECO:0000313|EMBL:AJP04201.1, ECO:0000313|Proteomes:UP000032234};
RN   [1] {ECO:0000313|EMBL:AJP04201.1, ECO:0000313|Proteomes:UP000032234}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NMWT 1 {ECO:0000313|EMBL:AJP04201.1,
RC   ECO:0000313|Proteomes:UP000032234};
RA   Wang H., Li C., Xiang W., Wang X.;
RT   "Genome sequence of thermotolerant Streptomyces cyaneogriseus subsp.
RT   Noncyanogenus NMWT1, the producer of nematocidal antibiotics nemadectin.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP010849; AJP04201.1; -; Genomic_DNA.
DR   RefSeq; WP_044384716.1; NZ_CP010849.1.
DR   AlphaFoldDB; A0A0C5GI97; -.
DR   STRING; 477245.TU94_24770; -.
DR   KEGG; scw:TU94_24770; -.
DR   PATRIC; fig|477245.3.peg.5226; -.
DR   HOGENOM; CLU_009902_6_1_11; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000032234; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AJP04201.1};
KW   Protease {ECO:0000313|EMBL:AJP04201.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032234}.
FT   DOMAIN          38..166
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          191..374
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   462 AA;  48772 MW;  ED7615F054F98B84 CRC64;
     MTELATMDFH PQPQAGEPKP WAFPAPERGT LANGLTVLRC HRPGQQVVAV EVLLNAPLEA
     EPAGLDGVAT IMARAFSEGT DKHSAEEFAA ELERCGATLD AHADHPGVRL SLEVPASRLA
     KALGLVADAL RAPAFADSEV ERLVRNRLDE IPHELANPSR RAAKELSKEL FPADSRMSRP
     RQGTEETVAN IDSAAVRAFY ERHVRPATAT AVVVGDLTGV DLDALLGDTL GAWTGSPAEP
     RPVPPVVADD TGRVVIVDRP GAVQTQLLIG RTGPDRHDRV WPAQVLGTYC LGGTLTSRLD
     RVLREEKGYT YGVRAFGQVL RSAPDGTGAA MLAISGSVDT PNTGPALADL WTVLRTLAAE
     GLTDAERDVA VQNLVGVAPL KYETAAAVAG TLADQVEQHL PDDYQAELYR QLAATGTVEA
     TAAVVNAFPV DRLVTVLVGD AAQIKAPVEA LGIGEVTVVA AE
//