ID   A0A0C7MWV2_9SACH        Unreviewed;       528 AA.
AC   A0A0C7MWV2;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=lysine--tRNA ligase {ECO:0000256|ARBA:ARBA00013166};
DE            EC=6.1.1.6 {ECO:0000256|ARBA:ARBA00013166};
DE   AltName: Full=Lysyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030563};
GN   ORFNames=LALA0_S04e08438g {ECO:0000313|EMBL:CEP62126.1};
OS   Lachancea lanzarotensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1245769 {ECO:0000313|EMBL:CEP62126.1, ECO:0000313|Proteomes:UP000054304};
RN   [1] {ECO:0000313|EMBL:CEP62126.1, ECO:0000313|Proteomes:UP000054304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 12615 {ECO:0000313|EMBL:CEP62126.1,
RC   ECO:0000313|Proteomes:UP000054304};
RA   Neuveglise Cecile;
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00008226}.
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DR   EMBL; LN736363; CEP62126.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C7MWV2; -.
DR   STRING; 1245769.A0A0C7MWV2; -.
DR   HOGENOM; CLU_008255_6_0_1; -.
DR   OrthoDB; 648039at2759; -.
DR   Proteomes; UP000054304; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004824; F:lysine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0006430; P:lysyl-tRNA aminoacylation; IEA:InterPro.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR004364; Aa-tRNA-synt_II.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR002313; Lys-tRNA-ligase_II.
DR   InterPro; IPR018149; Lys-tRNA-synth_II_C.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR00499; lysS_bact; 1.
DR   PANTHER; PTHR42918:SF5; LYSINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42918; LYSYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF00152; tRNA-synt_2; 1.
DR   PRINTS; PR00982; TRNASYNTHLYS.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054304}.
FT   DOMAIN          201..528
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
SQ   SEQUENCE   528 AA;  59312 MW;  9C83BEAD03C5B347 CRC64;
     MLGRSLTSRL RAASRSLQTH HTVDFTARNE AISQNQNLFY PSLSKLEAAT SSIAHFKQKY
     ANLKTDDTNA REVLRARISS IRLAGKNMCF IDVGNAQNST QLILNYNVML QHTHDTKIPP
     LTKEAFFQHV QGLKPGDHIQ APGFPGLSQR ERTLSLKCTQ MVQILAPALQ ALPPKLNDLV
     KRNQNRALDY QVNGYTSLIT RHRILSAIRE FLNSRSFLEV ETPILSPKSN GAAARAFVTR
     AQSTQKTLEL RVAPELWLKR LIVGGLDRIY EIGKVFRNEG VDATHSPEFT TLEFYQSYAS
     MEDLIALSEK LYMHVLNSVD TPIARKLKDA FENNGTKFNR VEFLPTLLQE TGVDLRNVDL
     SNSDDIEAAF SSKGINIEAN GKSPQQILNI VCGRFIETKH CMGMIPTLIY HHPTIMSPLA
     KGNPDDNLFT SKRFEVFIHG KEYINAYEEE NSPVLQLQKF IAQQEAHDNY GDDESLAVDT
     GYVEAMKWGM PPIGGFGLGI DRLCMLLTGN SRIERVLSFG TIDDVERQ
//