ID A0A0C7N6M3_9SACH Unreviewed; 323 AA.
AC A0A0C7N6M3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
GN ORFNames=LALA0_S02e04962g {ECO:0000313|EMBL:CEP61021.1};
OS Lachancea lanzarotensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=1245769 {ECO:0000313|EMBL:CEP61021.1, ECO:0000313|Proteomes:UP000054304};
RN [1] {ECO:0000313|EMBL:CEP61021.1, ECO:0000313|Proteomes:UP000054304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 12615 {ECO:0000313|EMBL:CEP61021.1,
RC ECO:0000313|Proteomes:UP000054304};
RA Neuveglise Cecile;
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MYST (SAS/MOZ) family.
CC {ECO:0000256|ARBA:ARBA00010107}.
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DR EMBL; LN736361; CEP61021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C7N6M3; -.
DR STRING; 1245769.A0A0C7N6M3; -.
DR HOGENOM; CLU_011815_0_2_1; -.
DR OrthoDB; 118560at2759; -.
DR Proteomes; UP000054304; Unassembled WGS sequence.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.60.60; N-acetyl transferase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002717; HAT_MYST-type.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10615; HISTONE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR10615:SF180; HISTONE ACETYLTRANSFERASE SAS2; 1.
DR Pfam; PF01853; MOZ_SAS; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51726; MYST_HAT; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000054304};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 17..304
FT /note="MYST-type HAT"
FT /evidence="ECO:0000259|PROSITE:PS51726"
FT REGION 53..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 228
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR602717-51"
SQ SEQUENCE 323 AA; 37579 MW; A38DC588DEED5235 CRC64;
MEKKGKRAVK EELYGIIETR NIEYVQYGVS LRFPTWYGST AYFQQTTRHL GLRDSDGRRS
AGDGIDEKPK SSRNVPESSD FWLETLCVCE YCFKYTDDPN ELKKHSSQCR FRSKSPGRIQ
YRTPEISIRK VSGSRHPLFC QCLCLFTKLF LDNKSMYFKV DHYDFYIVYS NQTHKPMAFF
SKDLTSFQKH NLACILTLPP YQRKGLGTLL MDFSYKLSIH DDIMSGPEQP LSPFGLAGYL
KYWSTSICLQ FLEGSLQGKS RVSLEDISKA TGMRLGDILL TLRNLNCLSE KNEISLQELR
LWMKHHRQHT HAFIDDDYLI LDD
//
