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Database: UniProt
Entry: A0A0C9M382_SPHPI
LinkDB: A0A0C9M382_SPHPI
Original site: A0A0C9M382_SPHPI 
ID   A0A0C9M382_SPHPI        Unreviewed;       514 AA.
AC   A0A0C9M382;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   05-JUL-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:GAN14220.1};
GN   ORFNames=SP6_33_00220 {ECO:0000313|EMBL:GAN14220.1};
OS   Sphingomonas paucimobilis NBRC 13935.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1219050 {ECO:0000313|EMBL:GAN14220.1, ECO:0000313|Proteomes:UP000032025};
RN   [1] {ECO:0000313|EMBL:GAN14220.1, ECO:0000313|Proteomes:UP000032025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 13935 {ECO:0000313|EMBL:GAN14220.1,
RC   ECO:0000313|Proteomes:UP000032025};
RA   Hosoyama A., Hashimoto M., Hosoyama Y., Noguchi M., Uohara A.,
RA   Ohji S., Katano-Makiyama Y., Ichikawa N., Kimura A., Yamazoe A.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Sphingomonas paucimobilis NBRC
RT   13935.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAN14220.1}.
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DR   EMBL; BBJS01000033; GAN14220.1; -; Genomic_DNA.
DR   EnsemblBacteria; GAN14220; GAN14220; SP6_33_00220.
DR   Proteomes; UP000032025; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032025};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032025}.
FT   DOMAIN      210    344       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      422    491       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     218    225       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   514 AA;  56791 MW;  D25A6F9718ECBF72 CRC64;
     MTNWQATRPT SDQARAWARV RANLRESAGA RLFDQWLKPM ELIEGDEPDT VRLALPSAFA
     TNWVRSHYAD RLHLEFKAVL PEVRAVMIET RAPSRAAKLT SVETLDATPA PRAAVSRVEV
     SPEPVESDDQ PSLFAVPTPA KPARPAPAPA PATRAAKVAS VAPVPAVPLR SASDRPPLDP
     RLTFDRFVVD SSNRVAFNAA LSLAEPGLPR FSPLFLHGGT GQGKTHLMHA IAHAFLESHP
     EAVVLCMSAE RFMFDFVAAM RARDTHSFKT RLRSADLLLI DDLQFIAGKD STQEEFFHTV
     NELVSAGKRL VISADRSPQS LDGVEPRIIG RLGAGLVADI KAPDLTLRRT ILNRKVSDLP
     DIVVPNDVLD LLASRIRGNI RELEGALNRV VAYAQLTGEK IDLEFAVATL GEVLRGAQRR
     ITIDEIQKLV SRHFELKPLD LVSARRARAI ARPRQIAMYL AKRLTTRSLP EIGRKFGGRD
     HSTVIYAVRK IEELRDTDRD IDNAVRVLMK ELEG
//
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