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Database: UniProt
Entry: A0A0C9M6K3_9FUNG
LinkDB: A0A0C9M6K3_9FUNG
Original site: A0A0C9M6K3_9FUNG 
ID   A0A0C9M6K3_9FUNG        Unreviewed;       826 AA.
AC   A0A0C9M6K3;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   22-NOV-2017, entry version 11.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=MAM1_0021c01852 {ECO:0000313|EMBL:GAN02409.1};
OS   Mucor ambiguus.
OC   Eukaryota; Fungi; Mucoromycota; Mucoromycotina; Mucorales; Mucorineae;
OC   Mucoraceae; Mucor.
OX   NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN02409.1, ECO:0000313|Proteomes:UP000053815};
RN   [1] {ECO:0000313|Proteomes:UP000053815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 6742 {ECO:0000313|Proteomes:UP000053815};
RA   Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S.,
RA   Koike H.;
RT   "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT   ambiguus NBRC6742.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; DF836310; GAN02409.1; -; Genomic_DNA.
DR   EnsemblFungi; 0; 0; MAM1_0021c01852.
DR   EnsemblFungi; GAN02409; GAN02409; MAM1_0021c01852.
DR   Proteomes; UP000053815; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053815};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053815};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    414    438       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    459    478       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    537    557       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    569    591       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    639    656       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    760    786       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       89    130       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   826 AA;  94509 MW;  5EC398AA0D6FFDAF CRC64;
     MAPSTLFRSE EMSLIQLYIP AEVAQPCVAE LGELGKVQFR DLNPEVNAFQ RSFVSEIRRL
     DEMERFFQTQ LAKSDIQVRP LTPAAYRSRA RSAQEVDDLE ENLKEYEGRI SQMNSSYESL
     QRRYLQLTEL RHVLRESAGF FEQAESRQDT IRNSLDIQDD SAPLLENDVE QNNYDSENLH
     LGYVTGVISR ARMQTFERVL WRSLRGNLYM KSAEIDEPIV DPDTDSVVDK NVFCIFAHGT
     EIIAKIKKIS ESLGGTLYTI DDSADKRRDS LLEVTSRIED LNNVLSTTNQ TRRSELLKVS
     ENVTAWTTIV RKEKAIYHTM NLFNYDVNRK CLIAEGWCPT NDIPLVQQSL KEATDASGTS
     LPSILTELHT KKTRPTYHRT NKFTEGFQGI IDAYGIARYR EVNPGLFTIV SFPFLFAMMF
     GDIGHGALLF LTALYLCLNE KKLASNNGEI FKMFFGGRYM MLMMGIFSIF TGAVYNDIFS
     LSLNVFKSGF DLPSNYTSFE SVEALPNGNV YAFGFDPAWH GSENFLLFSN SYKMKQAIVI
     GVIHMSFAVC LNVFNHIYYK RKAFVWLEFL PQILFMESIF GYLIFCIMYK WSVNWWELDS
     NGHHIRNAPP NLLNMLIYMF LTPGSVNPEE QLYPGQGPVQ LFLILLAVVC VPWMWFGKPF
     YLKKEASKHH YETVAGDDNA DEEEQAVAGT SNEDDEEEEE FEFSEVMIHQ TIHTIEFCLN
     CISNTASYLR LWALSLAHAQ LSSVLWDMTL KIWFNMTGPI AVIGLVIGFA MWFVLTIGIL
     LCMEGLSAFL HALRLMWVEF DGKFYNGDGI NFEPFTFATI LEPASE
//
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