ID A0A0C9MZ57_9FUNG Unreviewed; 497 AA.
AC A0A0C9MZ57;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Sorting nexin MVP1 {ECO:0000256|ARBA:ARBA00014268};
GN ORFNames=MAM1_0229d08401 {ECO:0000313|EMBL:GAN08882.1};
OS Mucor ambiguus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN08882.1};
RN [1] {ECO:0000313|EMBL:GAN08882.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN08882.1};
RA Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT ambiguus NBRC6742.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for vacuolar protein sorting.
CC {ECO:0000256|ARBA:ARBA00002474}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; DF836518; GAN08882.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9MZ57; -.
DR STRING; 91626.A0A0C9MZ57; -.
DR OrthoDB; 45524at2759; -.
DR Proteomes; UP000053815; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06866; PX_SNX8_Mvp1p_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR028662; SNX8/Mvp1.
DR InterPro; IPR035704; SNX8/Mvp1_PX.
DR InterPro; IPR045734; Snx8_BAR_dom.
DR PANTHER; PTHR47554; SORTING NEXIN MVP1; 1.
DR PANTHER; PTHR47554:SF1; SORTING NEXIN MVP1; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF19566; Snx8_BAR_dom; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053815};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 122..231
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 63..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 408..435
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 70..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 57758 MW; BB9C6746E2C0A0AA CRC64;
MQIVVPNGAS YVTQSEFNTA IALLACAQNK IDVSLQSLYR NRNYLPEPSM HNAEVVKSPL
KVMDDNPIAP EPTTKSNYQS KTAYPGMLKS SNEQQQKQQQ QQTEQEQTNN SKTLDTHHWF
QHLEEITVTV APEREGFIFK HVNYIVTNEK RSSIVLRRYS DFWWLLEVLL RRYPFRALPN
LPPKKLGGRD ATFLEKRRKG LSRFINAIIR HPVLRQDDIV ARFLTEPSEL SAWRKQNPPN
LDEEFKRKTH TIRDLDDMTP MNLDEQLQKA RKRVSAGINH YVNLCFIMER MIRRMHGQAT
DFSRYSIALN SLAEAELRYH AGECRNCQHV VKGYETVAKH MQTESSILED QVGSATDGVL
ENLKRFRDLL VSFRDLDERK AKLSANQTEM ISKRVAANRS KVHQNKGVPG LEAEVEKLEE
SIRADEMELT LQQDREIFIR FCMWSELIYL HKQQAFVSSL YQSYVTDSIA FSKLRATNWQ
DLETPAFEMP TNVELFE
//
