ID   A0A0C9N4E9_9FUNG        Unreviewed;       986 AA.
AC   A0A0C9N4E9;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   22-FEB-2023, entry version 30.
DE   RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN   ORFNames=MAM1_0435d10497 {ECO:0000313|EMBL:GAN10947.1};
OS   Mucor ambiguus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX   NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN10947.1};
RN   [1] {ECO:0000313|EMBL:GAN10947.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN10947.1};
RA   Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT   "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT   ambiguus NBRC6742.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC       {ECO:0000256|ARBA:ARBA00011276}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the EMC1 family.
CC       {ECO:0000256|ARBA:ARBA00007904}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DF836724; GAN10947.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C9N4E9; -.
DR   STRING; 91626.A0A0C9N4E9; -.
DR   OrthoDB; 37872at2759; -.
DR   Proteomes; UP000053815; Unassembled WGS sequence.
DR   GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR026895; EMC1.
DR   InterPro; IPR011678; EMC1_C.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR   Pfam; PF07774; EMC1_C; 1.
DR   Pfam; PF13360; PQQ_2; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053815};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..986
FT                   /note="ER membrane protein complex subunit 1"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002216023"
FT   TRANSMEM        956..976
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          776..985
FT                   /note="ER membrane protein complex subunit 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07774"
SQ   SEQUENCE   986 AA;  111354 MW;  0C54A6B5F23370D7 CRC64;
     MMNILNTLLL GLLLLQVALP TTAIYENQAG LFDWHHTWVG HPREAVKIDH NHIAVYSERN
     IIASLNTHTG AVEWRQVLDN QLDHFAATEA GILTISSNPE RAQFWNNTNG QLIWEQTPAE
     NESYGNTKPI VWDNGDVAVF VDRTKLVRLS KDGKELWTWT REANEAQVFE RLRASERGDL
     IYVIVEPNDD SRSPFFLVNV IYATTGETSS TFKIPCSANY EDVTYTGDYL LWTEEGVLKW
     TPINKKDISS VSIKSLVKAL PTADKFVPSK ISLFGGDDAQ LASFILSTEF EDDEETLFSA
     SVLVDIQEKT LKLNEYYGEH TAYGGADFFK QSTIRAVKSG AQELTVQVVP DEKEFKIKHD
     FSLSGEINYI KLINMDPFRL FVVTDGSSVF LYNESSIVWS REEALSGIAA SEFLDLPEQK
     MWTQMADELD ETASEQAAES PLSRYIRRLT THTLELRRLP SWIVSHFVGM SSSTLKNGNN
     KVSSLEAQSC WLNQTEPEVL YRDNFGLRKL LISVTNSGKI IAQDTSRNGK IVWSRYVDAF
     SFTQLHVVRA AAVKLPPVIV AVGNTYDEMG GQAVGFVRLN ALTGENYITA IPEIADFFEP
     VVATNIGVDK VMRLPIEDPD ERTHILAIYE AGSGRVYIYP DTMASQQKFV SEFLPTFYFS
     TQNADGSMQG FKVVEGYRGS LKVEPVWKFS LPQDEKTVTL SHKQPNEKVA SLGRALGNRN
     VLYKYLNPHM FALITKNAEK RLIKIRIMDS VKGSILYETI HENVDVEYND VHVIQSENWF
     VYHFWSNDAK ARGYQTAVLE LFEGEHENER VESANFSSFD NIEPRVLSSA FAFPYPVTTL
     GVTITRNGIS TKDILFGLPT HQIMGVNKRL FDPRRPKDKP TKEDQEEQLF PYSPIPDEKR
     LFLTYGLDVA GVKSIITSPS LLESTALVFA YGIDSFFTRS SPSKQFDVLS EDFSKFQLLL
     TITGLVVGIW VTGPMVRRKR VNALWK
//