ID A0A0C9THF2_PAXIN Unreviewed; 610 AA.
AC A0A0C9THF2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Xaa-Pro aminopeptidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PAXINDRAFT_169294 {ECO:0000313|EMBL:KIJ15105.1};
OS Paxillus involutus ATCC 200175.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Paxilineae; Paxillaceae; Paxillus.
OX NCBI_TaxID=664439 {ECO:0000313|EMBL:KIJ15105.1, ECO:0000313|Proteomes:UP000053647};
RN [1] {ECO:0000313|EMBL:KIJ15105.1, ECO:0000313|Proteomes:UP000053647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200175 {ECO:0000313|EMBL:KIJ15105.1,
RC ECO:0000313|Proteomes:UP000053647};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200175 {ECO:0000313|Proteomes:UP000053647};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; KN819338; KIJ15105.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9THF2; -.
DR HOGENOM; CLU_011781_2_3_1; -.
DR OrthoDB; 869at2759; -.
DR Proteomes; UP000053647; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763:SF21; X-PRO AMINOPEPTIDASE; 1.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053647}.
FT DOMAIN 14..146
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 323..537
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 550..609
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 610 AA; 67674 MW; 9A732A32911A60CB CRC64;
MGVIGTARVD TSERLASLRA LMREQDYNVG VFVVPSEDEH FSEYPSQADE RRTFISGFNG
SAGCAIITLQ NAFLFTDGRY FLQAEQQLDK NWNLMKQGLP DVPTWQEFLS KNIEQGTRIG
VDPSLISAVD AQVLKRSLGD SELVPLLKNP VDVVWASDRP QRPKNKVFVL DVEYSGETLS
TKLQRVREAM AKKNAVAMAV TLLDEVAWLF NLRGTDIDFN PVFFAYAVVE KDLAVLFVDE
AQVDDVVKAH LGQEVLIKPY TEFLPYLGAL AEKGLVQKEQ PVLLGDKTNL AVVHVLGEEN
VAIVPSPVAD MKAIKNSTEI NGFRQCHIRD GAALVRYFAW LDQQLKNGVV LSESQGADKL
EEFRSEFDLF RGLSFPTISS AGPNAGIIHY SPDPKDCATI TKDQIYLCDS GGQYLDGTTD
VTRTWHFGTP SAEEKRAFTR VLQGHIAIDT AIFPTGTTGF IIDSWARRAL WQDGLDYRHG
TGHGVGHFLN VHEGPQGIGT RIAYNSTPLK AGMTVSNEPG YYADGRWGIR IENVVIVCEV
ETPNNFGNGY LGFERVTMCP IQTSLIDYAI LTAEEKKWLN DYHAEVARKV GPLLQDECAL
AWLVKQCQAV
//
