ID A0A0D0S495_9FIRM Unreviewed; 300 AA.
AC A0A0D0S495;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Transcription regulator (Contains diacylglycerol kinase catalytic domain) {ECO:0000313|EMBL:KIR01167.1};
GN ORFNames=P261_02877 {ECO:0000313|EMBL:KIR01167.1};
OS Lachnospiraceae bacterium TWA4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1392836 {ECO:0000313|EMBL:KIR01167.1, ECO:0000313|Proteomes:UP000032079};
RN [1] {ECO:0000313|EMBL:KIR01167.1, ECO:0000313|Proteomes:UP000032079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TWA4 {ECO:0000313|EMBL:KIR01167.1,
RC ECO:0000313|Proteomes:UP000032079};
RX PubMed=25495654;
RA Gagen E.J., Wang J., Padmanabha J., Liu J., de Carvalho I., Liu J.,
RA Webb R.I., Al Jassim R., Morrison M., Denman S.E., McSweeney C.S.;
RT "Investigation of a new acetogen isolated from an enrichment of the tammar
RT wallaby forestomach.";
RL BMC Microbiol. 14:314-314(2014).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the diacylglycerol/lipid kinase family.
CC {ECO:0000256|ARBA:ARBA00005983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIR01167.1}.
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DR EMBL; JPZU01000004; KIR01167.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D0S495; -.
DR STRING; 1392836.P261_02877; -.
DR PATRIC; fig|1392836.3.peg.3261; -.
DR OrthoDB; 142078at2; -.
DR Proteomes; UP000032079; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR005218; Diacylglycerol/lipid_kinase.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR NCBIfam; TIGR00147; YegS/Rv2252/BmrU family lipid kinase; 1.
DR PANTHER; PTHR12358:SF106; LIPID KINASE YEGS; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KIR01167.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000032079};
KW Transferase {ECO:0000313|EMBL:KIR01167.1}.
FT DOMAIN 1..134
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 300 AA; 33290 MW; 6393B8BFAC9BEACB CRC64;
MSNKKMLFIF NPYSGKGQIK NNLVSILDTF IKAKYQINVH VTQEKGEATR IVRERAQDVD
YVVCSGGDGT LHEVVNGVMS LPSEERPSIG YIPTGTTNDY GKSLKIPKDM KKAALMMAKC
PSYLTDIGQF NDQYFTYVAG FGIFTAVSYT TPQDAKNMLG HPAYIIEGMK SLADIEPCHV
KVISDEYSEE GDYLIGLVTN SISVSGSKLV PGKGAILDDG IFEVMLVKNP ENPLAMPQVL
MEFLQDNPEN NSYVIRFKTS HIKFEVDKKI DWVLDGEFGG HLAEVDIQVK QKALAITRKN
//
