ID A0A0D1CYE8_USTMA Unreviewed; 2303 AA.
AC A0A0D1CYE8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=UMAG_01264 {ECO:0000313|EMBL:KIS71363.1};
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631 {ECO:0000313|EMBL:KIS71363.1, ECO:0000313|Proteomes:UP000000561};
RN [1] {ECO:0000313|EMBL:KIS71363.1, ECO:0000313|Proteomes:UP000000561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021 {ECO:0000313|Proteomes:UP000000561};
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kamper J., Kahmann R., Bolker M., Ma L.J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Muller O., Perlin M.H., Wosten H.A.,
RA de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G., Snetselaar K., McCann M.,
RA Perez-Martin J., Feldbrugge M., Basse C.W., Steinberg G., Ibeas J.I.,
RA Holloman W., Guzman P., Farman M., Stajich J.E., Sentandreu R.,
RA Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J.,
RA Mendoza-Mendoza A., Greilinger D., Munch K., Rossel N., Scherer M.,
RA Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S.,
RA Ho E.C., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J., Deelstra H.J.,
RA Ortiz-Castellanos L., Li W., Sanchez-Alonso P., Schreier P.H.,
RA Hauser-Hahn I., Vaupel M., Koopmann E., Friedrich G., Voss H., Schluter T.,
RA Margolis J., Platt D., Swimmer C., Gnirke A., Chen F., Vysotskaia V.,
RA Mannhaupt G., Guldener U., Munsterkotter M., Haase D., Oesterheld M.,
RA Mewes H.W., Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.,
RA Jaffe D.B., Calvo S., Nusbaum C., Galagan J., Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2] {ECO:0000313|Proteomes:UP000000561}
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021 {ECO:0000313|Proteomes:UP000000561};
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM003141; KIS71363.1; -; Genomic_DNA.
DR RefSeq; XP_011387188.1; XM_011388886.1.
DR STRING; 237631.A0A0D1CYE8; -.
DR EnsemblFungi; KIS71363; KIS71363; UMAG_01264.
DR GeneID; 23562344; -.
DR KEGG; uma:UMAG_01264; -.
DR VEuPathDB; FungiDB:UMAG_01264; -.
DR eggNOG; KOG1198; Eukaryota.
DR InParanoid; A0A0D1CYE8; -.
DR OMA; CQANGAH; -.
DR OrthoDB; 1448718at2759; -.
DR Proteomes; UP000000561; Chromosome 2.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000561}.
FT DOMAIN 1972..2300
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 862..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 968..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1353..1531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1554..1574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1597..1811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1840..1926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..583
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..887
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1177..1210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1353..1381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1464..1523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1607..1646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1663..1727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1750..1781
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1791..1806
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1873..1910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2303 AA; 243778 MW; 66D0DBC744485A2B CRC64;
MSKHSFMDTI LNRPSQRYTE PDAAKSSSKA RYKTPNDLPN APNKPNSILA GTMFTGAGPD
SLNHAAAASY SRAPSVMSVK SNTSRFSIFR KKTRQPSISG GSAYYDGSSS IAPTELAASP
RKGRWWESGT RNTYSSRPPS VAGSFFSEPE ATAPPGFPRI SDSLQANAPP RGARSDYGAT
SSTRKRYSSR SLQPPVPPLV HTASMSSMKR QSGVMPLGQQ QPNLMRQASS ISLARSPSNA
TPNAELQRPI SPPASIGNKS NQTRHAPNDS SDWNSFVKSM SGTEVAKMWE SMPTMAPKPP
RASEKRSSIV ANRVRKELEQ DAQFQQIQRD PGLLQQDLLA RAASQVIGAM PPTPVSPISE
PQMAPVHLQP GHVVAPISPI HSPIASHSSL QLVQHPQAML HQYSAPVPAT ALYQYTEAVS
APIPQQVAVA PLPAQVPVAS PALPPTSQNS SAQIYAPVAM PAASATTPPL ASPQHVKAVL
PPSIASAPQT LAQSAFETSI TFLPQPTLAH SPADHVEQQE SGDEQAQAQS EPSDESEDSD
DASSEERLVS GGQPALDVVA EEDEEVSSAG HDYHHEMRSR RPNKGNGLSR NYDNYEARLH
SRQVSAPSQQ DYFGDEEAPL VASGVQIHVT EPCDHEVLPM PNTEVAKQQV ETQHEAGNAE
PEPFAQEVPK PATASSTAAP ALASAAPRLV VPDKPPLVSR TSEFSDYQSA SSGRSTPTAK
RNDDDDDHKD GDAAVASTQN AEVVTKASRE SMSTDAASIA PSQHPSVRTT RSVRPGTVQR
RLSELSLGTS FAASGILRRP ESSRRNTDDS DSDKNLSDDD ADLRAQALAE QDRLRKMNVG
DDFFGPSFSS ILDKFDDFSS TDSAVSRLKR DPESQSVSAD RKHDAPPAES TALGIDVEAQ
KVINEVRQNR ANATVSENRR NSAETAVMAP SLAAVWLLNQ VQNTHDSSPA RELSDDAVDE
TITAPNVCSS NFVDVGSSPS AAGPQEPKVS VLNRPRPKAT RPHEMGGLSI SEGKLEAEKP
KSPVVVEDTR STLPVSISRS SIQSSETTTE FLQSTTVTPN KSSTVVASKD KPAPIKSALK
PKPSRSLADT LFSMSFRSPA KEKKEKKNKD KKKDKKDKTK HGRNTSVDSL GSASIQSQRS
SSMGSDPASV SAAPAATAET AAAPLSAKAL GKQRMTDDAD TANTTSKAAT TQQLDSMVPS
ETVNNFATPL QSMANLQTDA AAEVSPEKFH TAHDLTALAD TAVPVYPTNV ENVPPMPNGI
VSANARPDHQ RQLSEQMKSM ESFGSFTLPQ LDQHKVADSI LKRTEEAVAA AETVSSAVEG
DAAGGHVDAT GQAGSTDSAL ALSLPQNAGV DGVSIGNSTG TSSAPTMSEA SVASTALTSP
EVERASKAPE VDQAAATKAT MSQPTSDEAP SRVDLAEKKL PIPPPPGPEE VMASTHEDRT
PTGKPRAVSG VGINLIPPTP PALESRRSFT SSQVPGTPSI AENEETATTH QRPPLLSRSS
SQRTAVRGDT QPAGPSESLS RSKSMAPAKK GMWTEYKGKG LSLPPGLVAT TIDSSALRRM
STQDKRTSLQ PASMPSYAAA PALPVAPIVN QNVATAPLPL IESPSRPVRS IGSQSPRSKR
SIGSLGGSPQ SASVNRSGSL ATSPSMNRIM ADAPPVPQIP AGYQTAGSVS SSSSRLYTYS
VASSEQGWDS RSASPAPSAV PSQSARSIGS HVSSSVHSVS HRSSPKPEYS YVNHHELSPY
AKKMRSLSPS PAVPTLSQTG NRHSLMSAIN EWESQVPETE ASAAGLSPYP SRPTSPSPPP
SSSLYPPLPA STVSRASSVI SSMSSPAVVR NAPLGAATNQ YLSPPAARPR ISSDELAPAS
ESPIDSLSAP LVVGRPSGTS SVSSSSPSAS QSALSLPSTV QTSMPTVPTS YRPNKDPKRF
STNADGLLNN RTTMQTVAVT SGAFTSRSKS VVRRKKSVDL NGSPDMPEHL LDELSQTTLS
ITAHTPPPRK IGSQQVLVQV IAVAIDEMDK LLLREKVRAE NGFGYVPGRS FCGRIVECGY
EVKKMRKGDV VFGLQDSRKC GALSEFMVVD HNRICQAPSD CLTTEQIAAL PSAGVMAHQL
VQNHCSQLQR GARVLMLNAH DGVGLLTMQA SVGLGLVMVA QCPPSIADGV AVCQANGAHE
VVIGEPLWAI NSLHESSFDL IIDTVGGRKI YDASRRILGT DGQFCTCFGD EHGTANPNLK
SHLRSLRRAF FKKDKKNIGY EWVGVDTAED CREALEAVKI AAEQGAVCPR LRSVLPFSDA
GRAFDVDRRN ADDEPGAIVV RVS
//
