GenomeNet

Database: UniProt
Entry: A0A0D1M362_9LACT
LinkDB: A0A0D1M362_9LACT
Original site: A0A0D1M362_9LACT 
ID   A0A0D1M362_9LACT        Unreviewed;       470 AA.
AC   A0A0D1M362;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   05-JUL-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KIU22506.1};
GN   ORFNames=QX99_00009 {ECO:0000313|EMBL:KIU22506.1};
OS   Weissella cibaria.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Leuconostocaceae;
OC   Weissella.
OX   NCBI_TaxID=137591 {ECO:0000313|EMBL:KIU22506.1, ECO:0000313|Proteomes:UP000032287};
RN   [1] {ECO:0000313|EMBL:KIU22506.1, ECO:0000313|Proteomes:UP000032287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MG1 {ECO:0000313|EMBL:KIU22506.1,
RC   ECO:0000313|Proteomes:UP000032287};
RX   PubMed=25678547;
RA   Lynch K.M., Lucid A., Arendt E.K., Sleator R.D., Lucey B., Coffey A.;
RT   "Genomics of the Weissella cibaria species with an examination of its
RT   metabolic traits.";
RL   Microbiology (Mosc.) 0:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIU22506.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; JWHU01000001; KIU22506.1; -; Genomic_DNA.
DR   RefSeq; WP_043709388.1; NZ_JWHV01000023.1.
DR   STRING; 911104.WcibK1_010100005615; -.
DR   EnsemblBacteria; KIU22506; KIU22506; QX99_00009.
DR   PATRIC; fig|137591.25.peg.9; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   Proteomes; UP000032287; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032287};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032287}.
FT   DOMAIN      165    304       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      378    447       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     173    180       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   470 AA;  52737 MW;  C451F1C990F877AE CRC64;
     MDPVQLWNAI KEELRESIST GFSFANYVDT LTPLQVLENK NNTVTLHLST NHEQVADEWL
     NPSSSYYLAF MQAAMTATMK LYGQPTFIVP SVTYISPQPT SLFEVPATDA APEQQNATDT
     SPVAADFVTQ SILNPEFRFE TFVSSDENRE AYAVAQAVAD NPGTQWNPLL IYGGVGLGKT
     HLMQAIGNKV LENNPNAKVK FITTEDFIND FTEALRRGQK ETEAFKREYR STDLLLVDDV
     QFLAGKEKIQ EEFFNTFNAI TRENHQIVLT SDKLPKEIPG LEMRLVTRFG QGYSANITKP
     DLPTRVAILR NKSDQENLNI PNDVIDEIAA AVDTNVRDLE GVFNQVAGKL RFASQPVTVD
     TARDILETMN FKRQRAITIP IIQDTVAKFF DVTVQDLNGK KRNKEIVVPR QIAMYLAREL
     TQDSLPQIGR AFGGKDHTTV MHSTEKIDNA IENDALLADQ VQKIREELSN
//
DBGET integrated database retrieval system