ID   A0A0D1X684_9EURO        Unreviewed;      1105 AA.
AC   A0A0D1X684;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV11_05291 {ECO:0000313|EMBL:KIV83246.1};
OS   Exophiala sideris.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV83246.1, ECO:0000313|Proteomes:UP000053599};
RN   [1] {ECO:0000313|EMBL:KIV83246.1, ECO:0000313|Proteomes:UP000053599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV83246.1,
RC   ECO:0000313|Proteomes:UP000053599};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala sideris CBS121828.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   EMBL; KN846952; KIV83246.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D1X684; -.
DR   STRING; 1016849.A0A0D1X684; -.
DR   HOGENOM; CLU_003612_1_1_1; -.
DR   OrthoDB; 129892at2759; -.
DR   Proteomes; UP000053599; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053599}.
FT   DOMAIN          552..665
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          970..1075
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          438..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          727..963
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1076..1105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          337..368
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        442..466
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        727..757
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        810..839
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        840..859
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..963
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1105 AA;  122225 MW;  F3AC65D2AF443DB7 CRC64;
     MKQRYSSLDV KVIASELATS LVSLRVSNIY DLSSKIFLLK FAKPGKREQL LVDCGFRCHL
     TSFSRTAATA PSAFVSRLRK YLKSRRVTGV AQIGTDRVIE ITFSDGQYRL FLEFFAAGNM
     IVTDAELNVL ALQRQVSEGN EEVDVKLGGK YILDVKQNFH GIPPITPERV KESLAKAVER
     MKAANEVGGK KAKRAKGGDD LRKALSAGFS EFPPHLLDHV FNETGVNPSL KAEEVLENSE
     ALQSVIKALE RAEDVSKSLD ADKVKGYIIA KTKPSAVPEI GDHDTQTSPR DTLLYDDFHP
     FKPSQFENKS GVRLLEFDGF NRTVDEFYSS IESQKLESRL TEREEKAREK LQHAKNEHEK
     RIGALQHVQE LHVRKAQAIE ANTHRVEEAC AAVNGLIGQG MDWVDMGKLI EGEQQRGNVV
     AQLIKLPLKL EENTVTLLLD EPGFDDDNEE SSDEEKESDE DDISEDEPSP PPGKASDKRL
     AIDIDLALSP WANARQYYDQ KKTAAVKERK TLESSAKALQ SAEQKIGADL KKGLKQEKAG
     LRPARKQFWF EKFWYFISSD GYLVIGGKDA QQNELLYRRY LKKGDIYVHA DLQGASSVIV
     KNNPKTPDAP IPPTTLSQAG SLTVCTSSAW DSKALMGAWW VNADQVSKTA PTGEYLTTGG
     FIIRGKKNLL PPSQLLMGFG VMWLISEESR ANHGKHRLER TESMLSGEAE ALADDAQGLS
     LDEQDLAEEA EAASEQDEDA VPDLEDAADD AEEEEKEDAQ ATDVHVGDDG EEDDHEETGS
     VAASEPGEQR ANPLQSNVHD SRGAGTADEE EQEPEVEVEV ESDGDHEQEG DDDDEADGES
     SAQPSTPATP GSGVHPKPKQ QQLSRGKRSK AKRAQKKYAE QDEEDRALAM ELLGSARGQE
     RKKAVEDDKA AREAKAQADR ERRKAQHAKA AEKERLRHER LEKAAADGNT DLAEDDEQSK
     EQLEQERLEL LNIDRLVPFP QPGDELIAAV PIVAPWTAMA RQKYKIKLQP GNMKKGKAVK
     EILGFWVALD KKGPKVVDES SRDKERVWRR EIDLFKEWRP EEVVGYVPVK GCRIVQGGGI
     GTRPNVKGKG AAGGKGKGGG GKNRR
//