ID   A0A0D2A427_9EURO        Unreviewed;       604 AA.
AC   A0A0D2A427;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Glycolate oxidase, subunit GlcD {ECO:0000313|EMBL:KIW35026.1};
GN   ORFNames=PV07_01753 {ECO:0000313|EMBL:KIW35026.1};
OS   Cladophialophora immunda.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW35026.1, ECO:0000313|Proteomes:UP000054466};
RN   [1] {ECO:0000313|EMBL:KIW35026.1, ECO:0000313|Proteomes:UP000054466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW35026.1,
RC   ECO:0000313|Proteomes:UP000054466};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; KN847040; KIW35026.1; -; Genomic_DNA.
DR   RefSeq; XP_016255242.1; XM_016388314.1.
DR   AlphaFoldDB; A0A0D2A427; -.
DR   STRING; 569365.A0A0D2A427; -.
DR   GeneID; 27340947; -.
DR   VEuPathDB; FungiDB:PV07_01753; -.
DR   HOGENOM; CLU_017779_3_1_1; -.
DR   OrthoDB; 1664005at2759; -.
DR   Proteomes; UP000054466; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748:SF116; D-LACTATE DEHYDROGENASE (CYTOCHROME) (AFU_ORTHOLOGUE AFUA_7G02560); 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        92..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          178..355
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   REGION          36..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   604 AA;  66167 MW;  0BE0E88360DB3B58 CRC64;
     MKSIARLSRP VGSLLRCAER ERSSCFTPWA TRSFHSSPTK LEEKGKGDAK ENLSFRGQLY
     QSTADRLKRE RASEEQYIRA ATTRGGGAGG RTLSLSFVIL SVAAAAYYLG KRGERPLDAS
     STTPLSRAHP PQHDTRTSNL QAAWVDFAQI VGKDNVSTIP DDLEAHSGSE WSSYATKPNE
     RPFAIVYPAT TEEVSKIMKV CHERRIPVTA LSGGTSLEGH FAPTRGGICI DMARMDKILE
     LRPQDLDIVV QPALGWEDLN EELKGHGMFF PPDPGPGAKI GGMVGTGCSG TNAYRYGTMR
     DWVVSLTVVL ADGTIIKTRR RPRKSSAGYN LTQMFIGSEG TLGIVTEATL KITVLPKSQS
     VAVATFPTIH AAAECVARVV GEGIQLAGME ILDDVQMRCI NKSGMTSRPW QEAPTLFFKF
     AGTTEGVKEQ IKIIRNIAKG THNQSFEFAK NDDEAAELWS ARKEALWSVM AMRKNSSDHV
     WTTDVAVPIS RLADIIQETH DDVAKSGLIG GICGHVGDGN FHTILLYNDT EKKIAEELVH
     RMIRRAIAME GTVTGEHGVG LKKREYLREE LGDETVDAMR KLKQAFDPLG LLNCDKIVQI
     EAGH
//