ID   A0A0D2AGM5_9EURO        Unreviewed;       478 AA.
AC   A0A0D2AGM5;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   22-FEB-2023, entry version 30.
DE   RecName: Full=V-type proton ATPase subunit H {ECO:0000256|PIRNR:PIRNR032184};
GN   ORFNames=PV06_09071 {ECO:0000313|EMBL:KIW39286.1};
OS   Exophiala oligosperma.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW39286.1, ECO:0000313|Proteomes:UP000053342};
RN   [1] {ECO:0000313|EMBL:KIW39286.1, ECO:0000313|Proteomes:UP000053342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW39286.1,
RC   ECO:0000313|Proteomes:UP000053342};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase),
CC       a multisubunit enzyme composed of a peripheral complex (V1) that
CC       hydrolyzes ATP and a membrane integral complex (V0) that translocates
CC       protons. V-ATPase is responsible for acidifying and maintaining the pH
CC       of intracellular compartments. {ECO:0000256|PIRNR:PIRNR032184}.
CC   -!- SUBUNIT: V-ATPase is a heteromultimeric enzyme made up of two
CC       complexes: the ATP-hydrolytic V1 complex and the proton translocation
CC       V0 complex. {ECO:0000256|PIRNR:PIRNR032184}.
CC   -!- SIMILARITY: Belongs to the V-ATPase H subunit family.
CC       {ECO:0000256|ARBA:ARBA00008613, ECO:0000256|PIRNR:PIRNR032184}.
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DR   EMBL; KN847340; KIW39286.1; -; Genomic_DNA.
DR   RefSeq; XP_016259502.1; XM_016410480.1.
DR   AlphaFoldDB; A0A0D2AGM5; -.
DR   STRING; 215243.A0A0D2AGM5; -.
DR   GeneID; 27361145; -.
DR   VEuPathDB; FungiDB:PV06_09071; -.
DR   HOGENOM; CLU_025709_4_0_1; -.
DR   OrthoDB; 176803at2759; -.
DR   Proteomes; UP000053342; Unassembled WGS sequence.
DR   GO; GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; IEA:UniProtKB-UniRule.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 1.25.40.150; V-type ATPase, subunit H, C-terminal domain; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR004908; ATPase_V1-cplx_hsu.
DR   InterPro; IPR011987; ATPase_V1-cplx_hsu_C.
DR   InterPro; IPR038497; ATPase_V1-cplx_hsu_C_sf.
DR   PANTHER; PTHR10698; V-TYPE PROTON ATPASE SUBUNIT H; 1.
DR   PANTHER; PTHR10698:SF0; V-TYPE PROTON ATPASE SUBUNIT H; 1.
DR   Pfam; PF11698; V-ATPase_H_C; 1.
DR   Pfam; PF03224; V-ATPase_H_N; 1.
DR   PIRSF; PIRSF032184; ATPase_V1_H; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW   ECO:0000256|PIRNR:PIRNR032184};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|PIRNR:PIRNR032184};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053342};
KW   Transport {ECO:0000256|PIRNR:PIRNR032184}.
FT   DOMAIN          358..476
FT                   /note="ATPase V1 complex subunit H C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11698"
SQ   SEQUENCE   478 AA;  53719 MW;  A64BA6861F74A26B CRC64;
     MSLSPPAYLS SLQNNIRARP IPWDGAVRAG NLTDDQLKKI RSVDKVRKEQ RKQTIEKDVK
     SYSKLLVGGK DGGSVLEKAS KRSDIIQYIL VLATDLINDA PALADAILDH PEPYRPFISF
     LTQSGNPEDP IPLFSATFLV NLIAISLTSS SKPTPRDDQA LSQVYSYLAK LVKNQDSGLQ
     DIGVQHFSQL LRTSRSKELF WKQKSDTVDP LFDILRKAAG AAKDNDSTLW SGATSIRSSD
     TRFGGGVGLQ LMYHVLLVIW QLSFEGEMVG EGLEKDEEII PLYTQLLRMS PKEKTTRLLL
     ATLNNLLSSN KDTLIAIATT ARLPSLLSNL SGRHLTDQDL LEDLENLKTM LEEYTKNQTT
     FDEYADEVNS GHLRWSPPHR NPTFWRENAR KILEDKKGEL PKKLAEILSR GWESDKKVLA
     IGCNDVGNLV KEVPEHRSTL ERLGLKARLL ELMGDSDESV RWESLKAVGE WMRYTFDK
//