ID A0A0D2B0Y9_9EURO Unreviewed; 800 AA.
AC A0A0D2B0Y9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=3-dehydroquinate dehydratase, type I {ECO:0000313|EMBL:KIW45801.1, ECO:0000313|EMBL:KIW45802.1};
GN ORFNames=PV06_01513 {ECO:0000313|EMBL:KIW45801.1};
OS Exophiala oligosperma.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=215243 {ECO:0000313|EMBL:KIW45801.1, ECO:0000313|Proteomes:UP000053342};
RN [1] {ECO:0000313|EMBL:KIW45801.1, ECO:0000313|Proteomes:UP000053342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 72588 {ECO:0000313|EMBL:KIW45801.1,
RC ECO:0000313|Proteomes:UP000053342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala oligosperma CBS72588.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847333; KIW45801.1; -; Genomic_DNA.
DR EMBL; KN847333; KIW45802.1; -; Genomic_DNA.
DR RefSeq; XP_016266017.1; XM_016402120.1.
DR RefSeq; XP_016266018.1; XM_016402121.1.
DR STRING; 215243.A0A0D2B0Y9; -.
DR GeneID; 27353587; -.
DR VEuPathDB; FungiDB:PV06_01513; -.
DR HOGENOM; CLU_008871_0_1_1; -.
DR OrthoDB; 2106286at2759; -.
DR Proteomes; UP000053342; Unassembled WGS sequence.
DR GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:InterPro.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:InterPro.
DR CDD; cd00502; DHQase_I; 1.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR001381; DHquinase_I.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041121; SDH_C.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR022893; Shikimate_DH_fam.
DR PANTHER; PTHR21089:SF1; BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR21089; SHIKIMATE DEHYDROGENASE; 1.
DR Pfam; PF01487; DHquinase_I; 1.
DR Pfam; PF18317; SDH_C; 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053342}.
FT DOMAIN 486..566
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
FT DOMAIN 775..799
FT /note="SDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18317"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 89426 MW; 7A2826F98920FB4C CRC64;
MASRRPANPT STSSSDHRRG SLQEHPIPDF QTTLRHFDSR ASIALVGVRG AGKRSLGFIA
ATHLGRKFIS DGLYFEEVTG LSKAAYLHRY GKAEFQTRAL AIFQYMLAKN PQDCVIDCGM
ISVAAEAHEL LRHYSQTHPV IHIIRNYDHL SRHLQLGEQQ ARYLKETDLR LRECSNMEFY
NLYDSTCVAE TETSAEDFNQ TSSFVLQKIK IDIQAYVDFI LARDQSVPSS PFSQSALFPE
RKTRSYISFI RLSAMKKNPA ELDWAESGED AVELCIDTWE PGTTNDIAMW ISKLRRQLGI
RIVVSLAKSG TESSSPSHEA YWEMIRYILR LAVDYIVIDF NIPWAIQKAL LSSKGQTRTI
AEIHLDPDSP STWLGRERQI LCEKAQNLGY DLVRVTQFAT SRQDNQDSLQ FAIATSQTLK
IPIIAYNLGY LGRTSKVFNK IMTPVKRHEA DITNNHGDIP EAGVWLHQVC AALFQCFEYD
PLHFHVLGEL VSFSRAPAMY TVAFRLYGMR HEFSYRDVST FDEILTLARD HFFGGAALSY
PYKEIAFKAC TVTSPHASVI GSVNTIMPLR QLPGHKADAL AENARLRNRG GPVVGFYGDN
SDWEGLYNNI RRRLSPRNTA ACSRGAGLVL GAGGSSRSAV YALLRLGCQT VYVYNRTHAN
AVKLAAHFNT WCQTREGGSG KSSVVILEPE GTSWPQGTTL PTIIVSCVPI SVSLFGDSDL
PLQLPEEWLG SPSGGVVADI SYNPPETPLL KQIKSFREST GYPWAIVNGV DVVYEQAILQ
FEQFTGYRAP RQAMKDALKV
//
