ID A0A0D2C002_9EURO Unreviewed; 1618 AA.
AC A0A0D2C002;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=PV05_02573 {ECO:0000313|EMBL:KIW58021.1};
OS Exophiala xenobiotica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=348802 {ECO:0000313|EMBL:KIW58021.1, ECO:0000313|Proteomes:UP000054342};
RN [1] {ECO:0000313|EMBL:KIW58021.1, ECO:0000313|Proteomes:UP000054342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 118157 {ECO:0000313|EMBL:KIW58021.1,
RC ECO:0000313|Proteomes:UP000054342};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala xenobiotica CBS118157.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KN847318; KIW58021.1; -; Genomic_DNA.
DR RefSeq; XP_013318605.1; XM_013463151.1.
DR STRING; 348802.A0A0D2C002; -.
DR GeneID; 25324481; -.
DR HOGENOM; CLU_001640_2_0_1; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000054342; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054342};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 841..861
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1015..1036
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1057..1079
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1091..1111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1118..1140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1160..1184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1205..1222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..698
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1264..1491
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 768..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1618 AA; 177233 MW; 0C59AC4A5C54A7A2 CRC64;
MALFVRQVWT LILKNLLIAF VRRWFTTTIR AFLLPCIFVG FLSYARFLFI PPSVYGIGSP
ISVRDLPQAL DLVSGGRDKL VFVNNGFSDG PIQSVIDRVT SDAGSFSGKV EILSQEVDLL
TTCRNSIRGT STCIAGAVFF SSPSEGEAGR WNYSIRADGG LQNKIVTDSS KNDVEIYLLP
LQHAIDRAIS EVESGNNGSG TLPERVEEYP YTSMTKEQRL QQIRTRYMGG IIDILAVAFF
IGVVGVTYQL TGLIAAEREQ GMAQLLDCMM PNSKRWQPQM ARIVANHAAF DLLYGPGWII
MAIILSVGVF SKTSTAIVII FNILSGLAMS SLSIFGASFF KKAQLSGITS VITSLLLAII
AQVAGKAGTA SVAILSLLFP PMNYVYFVIF MARYERQNLG TNLVKQAPNN TSALPGIAFW
IFSVIQIVMY PILGAYVERA LYGTASKSRK TNYSDDTTAI SLVGFTKVYR PSIFAKLRAL
LWRKKPKTVL AVDQLSLDAI RGQIMVLLGA NGSGKSTTLD AIAGLNSITS GEIVINYPEA
NTGLGLCPQK NVLWDDLTVE EHVRIFNRIK SKTPASKDEN MSLLTSCDIV AKANARSKTL
SGGQKRKLQL AVMFTGGSRV CCVDEVSSGL DPLSRRKIWD ILLAERGTRS IILTTHFLDE
AELLADHIAI LSKGSLKASG TSVELKNRLG SGYRVHVYHT HGAQQLPTYQ EISHRRHGDQ
TIYSLNDSAE AAQFLNRIDS AGLAEYQVNG PTIEDVFLKV AEEVRSSHDT PQKVGLGNKL
QEVGSRSSDE ATSPSKAADV AIKDDSAADV PQLLDGRRIS MTRQAMALFS KRVVVLRRNT
LPYLAALLIP IIAAGLVTLF LKHFEKAECT PASAISISDI VSLSTQIDYQ LVAGPRDRLD
QRALEMLSGT FAGSTGAGGV AANTTRLLNS LHIVNTLDEF NDYIQNKFAN VTPGGFFLGD
SGSSPTFAWK GNGDIAFPVI VQNALDTLLT NISISNQYQA FDVPWGASVG DALQLITYFG
LAMAVYPSFF ALYPTIERLR NVRGLHYSNG VRSAPLWLAY TTFDFTIVVI TSAVAVIIFR
AASDVWYHIE YLFVVLFLYG LASTLLSYVI SLFSRSQLAA FAFAAGGQAV MFLLYFIAYM
SVLTYSPIDK IDQYVNISHF TIAAISPVAN LTRALFVTLN VFSITCRDRQ FASYPGSMTT
FGGPILYLIL QSVLLFGLLL WWDSGPLFRR LRGKQLEEEV ESKDTAEAEI SDELTRVNSS
QDGLRVLHLT KYFGKNLAVD NVTFGVPRSQ VFALLGRNGA GKSTTISLIR GDIQPSRRGG
DILVDDISVI RHRAQARSRL GVCPQFDAID TMTVAEHLHF YAKVRGVSDP RHNVEAVMRA
VGLEQYADRM AAKLSGGNKR KLSLGIALMG NPSVLLLDEP SSGMDAASKR VMWRTLESVV
PGRSLVLTTH SMEEADALAT RAGIMAGKML ALGTTDYLRR KHGDAYYVHL VHCQAPHASV
EDMERIRNWI VSTFPNADVE SKIYAGQIRF SVPTAGFRRD EDEISHGSGI SAVFTALEKN
KSELQIQYYS VSRATLDQVF LSIVGKHNVA EEGTETLVAP KHQGGNGLAR LFHIRRRR
//
