ID A0A0D2CR64_9EURO Unreviewed; 665 AA.
AC A0A0D2CR64;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Protection of telomeres protein 1 {ECO:0000256|ARBA:ARBA00015253};
GN ORFNames=PV07_00526 {ECO:0000313|EMBL:KIW33698.1};
OS Cladophialophora immunda.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=569365 {ECO:0000313|EMBL:KIW33698.1, ECO:0000313|Proteomes:UP000054466};
RN [1] {ECO:0000313|EMBL:KIW33698.1, ECO:0000313|Proteomes:UP000054466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 83496 {ECO:0000313|EMBL:KIW33698.1,
RC ECO:0000313|Proteomes:UP000054466};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora immunda CBS83496.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the telombin family.
CC {ECO:0000256|ARBA:ARBA00008442}.
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DR EMBL; KN847040; KIW33698.1; -; Genomic_DNA.
DR RefSeq; XP_016253914.1; XM_016386986.1.
DR AlphaFoldDB; A0A0D2CR64; -.
DR STRING; 569365.A0A0D2CR64; -.
DR GeneID; 27339720; -.
DR VEuPathDB; FungiDB:PV07_00526; -.
DR HOGENOM; CLU_016663_1_0_1; -.
DR OrthoDB; 1421338at2759; -.
DR Proteomes; UP000054466; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043047; F:single-stranded telomeric DNA binding; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR028389; POT1.
DR InterPro; IPR032042; POT1PC.
DR InterPro; IPR011564; Telomer_end-bd_POT1/Cdc13.
DR PANTHER; PTHR14513; PROTECTION OF TELOMERES 1; 1.
DR PANTHER; PTHR14513:SF0; PROTECTION OF TELOMERES PROTEIN 1; 1.
DR Pfam; PF02765; POT1; 1.
DR Pfam; PF16686; POT1PC; 1.
DR SMART; SM00976; Telo_bind; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022895};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054466};
KW Telomere {ECO:0000256|ARBA:ARBA00022895}.
FT DOMAIN 12..151
FT /note="Telomeric single stranded DNA binding POT1/Cdc13"
FT /evidence="ECO:0000259|SMART:SM00976"
FT REGION 373..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 76185 MW; 336840E9BD66E718 CRC64;
MASNFVPLPS DFVDLSNAYS VEANSKLINV IGVCVDFLSP TRCQNGRQDY KIKFTLHDPA
WPAGIGLPFS FFNKQLKQLP DIRDQGDVVI LRNVKINVFR GQTTGWSNAS STWVVLPAAE
LDNIQSAQDL KDKGRWMGQE YGDPNNYLQG AKVALANEAE LKYAKWIADQ EDPSLWSKQQ
PRTQLEIANT MEENGGTAPA RKEKFRTLDR LDLPVRRDCI FVDLLGEVRK IFSPNDLTTE
LYMTDYTTND RLHDYQHAGD QAGRDGDPFG YIQDKTSNKW PGPWGKMTIL VTCWGRQASV
AAQIAHLGSF VYLRNVQIKM DRNGSRLEGN CRDDRDYPDK ELIEVVKSGD EKRTELLRRK
RAYEQKVEGA GISFYRDPNQ ATKKRQKDEP TEQQNDEPKS KRTKARNRKN KKAKLEALQQ
EKKHAAVTIA RQEHSLLKSN NHIRCNQYEG VSCKPVIDIL DPDILNRMTA KGNPYRLPFQ
NCTYKSKVRV VDFFPDNIAD FAAPLRAGQY DELSDNEDFE EDWDIDPTQE RNPQDLKWEW
RFLLLVEDAR TPAGADGRPT QMELLVADTD GDFLLNMDAC DLRDKANQDE LAKLKEKLFH
LWGDLQERKE ESSTTTEELR VKPSARPFEC LIKEYGTSVL RPNRQAKDSV VYDRRFRLFG
TALAV
//
