ID   A0A0D2FET5_9EURO        Unreviewed;       392 AA.
AC   A0A0D2FET5;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=CobW/HypB/UreG nucleotide-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV04_05858 {ECO:0000313|EMBL:KIW66533.1};
OS   Phialophora macrospora.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX   NCBI_TaxID=1851006 {ECO:0000313|EMBL:KIW66533.1, ECO:0000313|Proteomes:UP000054266};
RN   [1] {ECO:0000313|EMBL:KIW66533.1, ECO:0000313|Proteomes:UP000054266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 27337 {ECO:0000313|EMBL:KIW66533.1,
RC   ECO:0000313|Proteomes:UP000054266};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capronia semiimmersa CBS27337.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR   EMBL; KN846959; KIW66533.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D2FET5; -.
DR   STRING; 5601.A0A0D2FET5; -.
DR   HOGENOM; CLU_017452_0_1_1; -.
DR   OrthoDB; 1010489at2759; -.
DR   Proteomes; UP000054266; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF31; COBW DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          33..236
FT                   /note="CobW/HypB/UreG nucleotide-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02492"
FT   DOMAIN          320..377
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07683"
SQ   SEQUENCE   392 AA;  42666 MW;  55E059483289A27F CRC64;
     MDDDDDEVPD LVEAEKNEII TNGSEVSPLK KVPITIVTGY LGAGKTTLLN YILTAEHGKK
     IAVILNEFGN TADIEKSLTV SQGDQSSTEW IPLANGCICC SVKDSGVAAL ESLVERQKNF
     DYILLETTGV ADPGNIAPMF WLDEGLGSSI YLDGIITVVD AKNILRSLDE PAPEEIPEDE
     KDAQHHDHET PLLTTAHLQI SHADVIILNK TDLVSDTKLS AVQTRISSIN GLARIIPTNH
     SHVDNLSGTI LDLHAYSTFP TAPSVNAMPD FASKGHSHLD PTLSTYTIPL PPFDPQKLPL
     LLGWLESLLW DAEDRQEGRG RKYEVHRTKG LIRCTDGTSR VVQGVREIFD LIEIPPTEDT
     EDTVTEGKIV FIGRNLDLIG GIDSDGVGTF SS
//