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Database: UniProt
Entry: A0A0D2HP11_9DELT
LinkDB: A0A0D2HP11_9DELT
Original site: A0A0D2HP11_9DELT 
ID   A0A0D2HP11_9DELT        Unreviewed;       441 AA.
AC   A0A0D2HP11;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   25-OCT-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=X474_19975 {ECO:0000313|EMBL:KIX12283.1};
OS   Dethiosulfatarculus sandiegensis.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfarculales;
OC   Desulfarculaceae; Dethiosulfatarculus.
OX   NCBI_TaxID=1429043 {ECO:0000313|EMBL:KIX12283.1, ECO:0000313|Proteomes:UP000032233};
RN   [1] {ECO:0000313|EMBL:KIX12283.1, ECO:0000313|Proteomes:UP000032233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SPR {ECO:0000313|EMBL:KIX12283.1,
RC   ECO:0000313|Proteomes:UP000032233};
RA   Davidova I.A., Callaghan A.V., Wawrik B., Pruitt S., Marks C.,
RA   Duncan K.E., Suflita J.M.;
RT   "Metagenomic analysis of a methanogenic consortium involved in long
RT   chain n-alkane degradation.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIX12283.1}.
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DR   EMBL; AZAC01000034; KIX12283.1; -; Genomic_DNA.
DR   EnsemblBacteria; KIX12283; KIX12283; X474_19975.
DR   PATRIC; fig|1429043.3.peg.4234; -.
DR   Proteomes; UP000032233; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032233};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032233}.
FT   DOMAIN      138    273       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      349    417       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     146    153       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   441 AA;  50168 MW;  1293C5EF4B8EEA56 CRC64;
     MSENRLWNHI IEDLQNRLER DDFDLWIKPL AAQMGANDNL TLLCPSRFHL KRLRETYLPM
     VNNFLENQGE QVKLNCKVAV PSNSRGENQS NRQMNLPSIK RGMPLLNNRF KFDRFVAGGG
     NELAFAAAKA LAGEKRFFSN TLLLVSDTGL GKSHLTQSVG HYVMETQPNA RVAYLTAEDF
     ANQMISALRR KNMDAFKEHF RRECDILLLE EIPFLAGKEK TQDELGFTLD ALLDAGKRII
     LTSCQVPNEI KGIKRNLESR ISSGMTINIE PPDHRTRVNI LAHQAHEEGM VVDPEVLEYL
     AQEIPEDIRR LQSSLVGIMA QGSLTNRPMD LGLAVEIVGK MTHRKKKVNV ETIRDMVARI
     YGMEISTLTS RSRRKVVTVP RNMAMYLCRK HTSASYATIG RSFNRDHATV MYGVNQIDRK
     IANDPKLQKE MSHIEQRLGV R
//
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